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NCT00759473 · ClinicalTrials.gov registry record · Phase 2
D-Cycloserine Facilitation of Cocaine - Cue Extinction
A Phase 2 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 79
- Enrollment target
NCT00759473: Completed Phase 2 study, sponsored by Medical University of South Carolina.
NCT00759473 is a Phase 2 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 79 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00759473, a Phase 2 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 79 participants
- Enrollment target
Study Summary
The purpose of this study is to explore the use of d-cycloserine (DCS) to facilitate extinction of response to cocaine cues in cocaine-dependent individuals, in hopes that it may lead to the development of new treatment options for cocaine dependence.
Primary Outcome
Average of participants' subjective measures of craving immediately following cue exposure at the one-week follow-up session. Participants rated craving on a 10 point analog scale ranging from 0 (not at all) to 10 (extremely).
Interventions
- DRUG Placebo
- DRUG D-Cycloserine (DCS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2008-09 |
| Est. Completion | 2011-10 |
| Phase | Phase 2 |
What the finished NCT00759473 record still lists
NCT00759473 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00759473 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00759473 about?
NCT00759473 is a clinical study titled "D-Cycloserine Facilitation of Cocaine - Cue Extinction". The purpose of this study is to explore the use of d-cycloserine (DCS) to facilitate extinction of response to cocaine cues in cocaine-dependent individuals, in hopes that it may lead to the development of new treatment options for cocaine dependence.
What is the current status of trial NCT00759473?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 79 participants. The study started on 2008-09. Estimated completion is 2011-10.
What interventions are being tested in trial NCT00759473?
The interventions under investigation include: Placebo (DRUG), D-Cycloserine (DCS) (DRUG).
Who is sponsoring clinical trial NCT00759473?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00759473's enrollment target sits among peer trials
79 884th of 2000 higher than 1,117 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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