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NCT00756262 · ClinicalTrials.gov registry record · Phase 1

Probiotic Lactobacillus GG to Eliminate VRE Colonization

A Phase 1 study, sponsored by Tufts Medical Center.

Terminated
Registry status
Phase 1
Development phase
11
Enrollment target

NCT00756262: Clinical Trial Phase 1 study, sponsored by Tufts Medical Center.

NCT00756262 is a Phase 1 study that was terminated before completion, run by Tufts Medical Center. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00756262, a Phase 1 study, was terminated before completion, sponsored by Tufts Medical Center.

TERMINATED
Registry status
Phase 1
Development phase
11 participants
Enrollment target

Study Summary

The use of LGG will be associated with elimination of VRE colonization. The primary comparison will be VRE elimination rates among those patients that receive LGG compared to those that receive placebo. The primary endpoint will be the proportion of patients with VRE at one week after cessation of administration of study medication or placebo. The investigators assume that the placebo group will have very little spontaneous elimination of VRE and that the LGG group will be more likely to have eliminated VRE colonization at the end of one week.

Interventions

  • BIOLOGICAL Lactobacillus GG or Culturelle

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2003-03
Est. Completion 2012-07
Phase Phase 1
Tufts Medical Center

169 total trials

Why NCT00756262 stopped before completion

NCT00756262 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 1 intervention - of which Lactobacillus GG or Culturelle is the first listed.

NCT00756262 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00756262 about?

NCT00756262 is a clinical study titled "Probiotic Lactobacillus GG to Eliminate VRE Colonization". The use of LGG will be associated with elimination of VRE colonization. The primary comparison will be VRE elimination rates among those patients that receive LGG compared to those that receive placebo. The primary endpoint will be the proportion of patients with VRE at one week after cessation of ...

What is the current status of trial NCT00756262?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2003-03. Estimated completion is 2012-07.

What interventions are being tested in trial NCT00756262?

The interventions under investigation include: Lactobacillus GG or Culturelle (BIOLOGICAL).

Who is sponsoring clinical trial NCT00756262?

This trial is sponsored by Tufts Medical Center, which has 169 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00756262's enrollment target sits among peer trials

11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00756262, the US trial registry maintained by the National Library of Medicine. NCT00756262 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.