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NCT00747617 · ClinicalTrials.gov registry record · Phase 3
Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
A Phase 3 study, sponsored by University of California, San Diego.
- Completed
- Registry status
- Phase 3
- Development phase
- 25
- Enrollment target
NCT00747617: Completed Phase 3 study, sponsored by University of California, San Diego.
NCT00747617 is a Phase 3 study that has completed, run by University of California, San Diego. The registered enrollment target is 25 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00747617, a Phase 3 study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 25 participants
- Enrollment target
Study Summary
The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH) secretion in this disorder. The investigators hypothesize that in PCOS women ovarian theca cells, which are responsible for androgen synthesis, are more sensitive to LH stimulation compared to that of theca cells from normal women. To test this hypothesis, the investigators propose to conduct a dose-response study in which androgen responses to multiple doses of human chorionic gonadotgropin (hCG), an LH surrogate, will be assessed in PCOS and normal women.
Primary Outcome
Assess serum 17OHP levels following each dose of hCG adminstration in PCOS and normal subjects
Interventions
- DRUG recombinant human chorionic gonadotropin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2007-09 |
| Est. Completion | 2010-09 |
| Phase | Phase 3 |
What the finished NCT00747617 record still lists
NCT00747617 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which recombinant human chorionic gonadotropin is the first listed.
NCT00747617 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00747617 about?
NCT00747617 is a clinical study titled "Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)". The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH) secretion in this disorder. The investigators hypothesize that in PCOS women ov...
What is the current status of trial NCT00747617?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 25 participants. The study started on 2007-09. Estimated completion is 2010-09.
What interventions are being tested in trial NCT00747617?
The interventions under investigation include: recombinant human chorionic gonadotropin (DRUG).
Who is sponsoring clinical trial NCT00747617?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00747617's enrollment target sits among peer trials
25 1941st of 2000 higher than 58 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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