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NCT00743119 · ClinicalTrials.gov registry record · Phase 2
Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
A Phase 2 study, sponsored by New York State Psychiatric Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 34
- Enrollment target
NCT00743119: Completed Phase 2 study, sponsored by New York State Psychiatric Institute.
NCT00743119 is a Phase 2 study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 34 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00743119, a Phase 2 study, has completed, sponsored by New York State Psychiatric Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 34 participants
- Enrollment target
Study Summary
The following study is designed to determine the analgesic efficacy of smoked marijuana (0, 1.98, and 3.56% THC) and oral THC (0, 10, and 20 mg) in the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive validity for clinical use of analgesics. Oral THC (dronabinol) is known to have a slower onset and longer duration of action compared with smoked marijuana. Therefore, the analgesic effects of oral THC is expected to peak later and last longer than effects produced by smoked marijuana.
Primary Outcome
Change in pain tolerance from baseline (in seconds) as a function of drug condition. The cold pressor test was administered during each session to examine changes in pain threshold (how many seconds it takes for a participant to begin feeling pain after cold water immersion).
Interventions
- DRUG Placebo capsules
- DRUG Inactive marijuana (0% THC)
- DRUG Low dose Dronabinol
- DRUG High dose Dronabinol
- DRUG Low THC marijuana
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2008-06 |
| Est. Completion | 2013-05 |
| Phase | Phase 2 |
What the finished NCT00743119 record still lists
NCT00743119 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo capsules is the first listed.
NCT00743119 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00743119 about?
NCT00743119 is a clinical study titled "Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers". The following study is designed to determine the analgesic efficacy of smoked marijuana (0, 1.98, and 3.56% THC) and oral THC (0, 10, and 20 mg) in the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive validity for clinical use of analgesics. Oral THC (dronabinol) is known to ...
What is the current status of trial NCT00743119?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2008-06. Estimated completion is 2013-05.
What interventions are being tested in trial NCT00743119?
The interventions under investigation include: Placebo capsules (DRUG), Inactive marijuana (0% THC) (DRUG), Low dose Dronabinol (DRUG), High dose Dronabinol (DRUG), Low THC marijuana (DRUG).
Who is sponsoring clinical trial NCT00743119?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00743119's enrollment target sits among peer trials
34 1539th of 2000 higher than 448 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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