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NCT00741234 · ClinicalTrials.gov registry record · Phase 1

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

A Phase 1 study, sponsored by S*BIO.

Completed
Registry status
Phase 1
Development phase
85
Enrollment target

NCT00741234: Completed Phase 1 study, sponsored by S*BIO.

NCT00741234 is a Phase 1 study that has completed, run by S*BIO. The registered enrollment target is 85 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00741234, a Phase 1 study, has completed, sponsored by S*BIO.

COMPLETED
Registry status
Phase 1
Development phase
85 participants
Enrollment target

Study Summary

This is an open label, dose escalation study with 3 arms (Arms A, B, and C). Arm A will assess the safety and tolerability of escalating doses of SB939 in cohorts of patients with advanced solid tumors. Arm B will assess the safety and tolerability of escalating doses in cohorts of patients with advanced hematologic malignancies. Arm C will assess the safety and tolerability of SB939 in combination with standard azacitidine therapy.

Interventions

  • DRUG Azacitidine
  • DRUG SB939

Trial Details

FieldValue
Enrollment Target 85 participants
Start Date 2007-04
Est. Completion 2012-03
Phase Phase 1
S*BIO

6 total trials

What the finished NCT00741234 record still lists

NCT00741234 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher).

The record links to 0 conditions, and to 2 interventions - of which Azacitidine is the first listed.

NCT00741234 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00741234 about?

NCT00741234 is a clinical study titled "A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine". This is an open label, dose escalation study with 3 arms (Arms A, B, and C). Arm A will assess the safety and tolerability of escalating doses of SB939 in cohorts of patients with advanced solid tumors. Arm B will assess the safety and tolerability of escalating doses in cohorts of patients with adv...

What is the current status of trial NCT00741234?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2007-04. Estimated completion is 2012-03.

What interventions are being tested in trial NCT00741234?

The interventions under investigation include: Azacitidine (DRUG), SB939 (DRUG).

Who is sponsoring clinical trial NCT00741234?

This trial is sponsored by S*BIO, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00741234's enrollment target sits among peer trials

85 656th of 2000 higher than 1,342 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00741234, the US trial registry maintained by the National Library of Medicine. NCT00741234 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.