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NCT00732082 · ClinicalTrials.gov registry record · Phase 1

Lag-3 and Gemcitabine for Treatment of Advanced Pancreas Cancer

A Phase 1 study, sponsored by Washington University School of Medicine.

Terminated
Registry status
Phase 1
Development phase
18
Enrollment target

NCT00732082: Clinical Trial Phase 1 study, sponsored by Washington University School of Medicine.

NCT00732082 is a Phase 1 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00732082, a Phase 1 study, was terminated before completion, sponsored by Washington University School of Medicine.

TERMINATED
Registry status
Phase 1
Development phase
18 participants
Enrollment target

Study Summary

The overall purpose of this research is to evaluate the safety and toxicity of an investigational medication, IMP321, in patients being treated with gemcitabine. IMP321 is a synthetic protein (made in the laboratory to simulate a protein that your body makes on its own) and was designed to stimulate the immune system with the overall objective of improving the body's capacity to react to your pancreas cancer.

Interventions

  • DRUG Gemcitabine
  • BIOLOGICAL LAG-3

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2009-02
Est. Completion 2012-09
Phase Phase 1

Why NCT00732082 stopped before completion

NCT00732082 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 2 interventions - of which Gemcitabine is the first listed.

NCT00732082 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00732082 about?

NCT00732082 is a clinical study titled "Lag-3 and Gemcitabine for Treatment of Advanced Pancreas Cancer". The overall purpose of this research is to evaluate the safety and toxicity of an investigational medication, IMP321, in patients being treated with gemcitabine. IMP321 is a synthetic protein (made in the laboratory to simulate a protein that your body makes on its own) and was designed to stimulate...

What is the current status of trial NCT00732082?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2009-02. Estimated completion is 2012-09.

What interventions are being tested in trial NCT00732082?

The interventions under investigation include: Gemcitabine (DRUG), LAG-3 (BIOLOGICAL).

Who is sponsoring clinical trial NCT00732082?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00732082's enrollment target sits among peer trials

18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00732082, the US trial registry maintained by the National Library of Medicine. NCT00732082 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.