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NCT00719836 · ClinicalTrials.gov registry record · Phase 1

A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignancies

A Phase 1 study, sponsored by S*BIO.

Completed
Registry status
Phase 1
Development phase
76
Enrollment target

NCT00719836: Completed Phase 1 study, sponsored by S*BIO.

NCT00719836 is a Phase 1 study that has completed, run by S*BIO. The registered enrollment target is 76 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00719836, a Phase 1 study, has completed, sponsored by S*BIO.

COMPLETED
Registry status
Phase 1
Development phase
76 participants
Enrollment target

Study Summary

This study consists of two phases: the first portion of the study is a Phase 1 dose escalation study to determine the maximum tolerated dose and the dose limiting toxicities of SB1518 when given as a single agent orally once daily in subjects with advanced myeloid malignancies; the second portion of the study is a Phase 2 study to define the efficacy and safety profile of single-agent SB1518 at the recommended dose in subjects with chronic idiopathic myelofibrosis (CIMF).

Interventions

  • DRUG SB1518

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2008-08
Est. Completion 2012-01
Phase Phase 1
S*BIO

6 total trials

What the finished NCT00719836 record still lists

NCT00719836 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher).

The record links to 0 conditions, and to 1 intervention - of which SB1518 is the first listed.

NCT00719836 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00719836 about?

NCT00719836 is a clinical study titled "A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignancies". This study consists of two phases: the first portion of the study is a Phase 1 dose escalation study to determine the maximum tolerated dose and the dose limiting toxicities of SB1518 when given as a single agent orally once daily in subjects with advanced myeloid malignancies; the second portion of...

What is the current status of trial NCT00719836?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2008-08. Estimated completion is 2012-01.

What interventions are being tested in trial NCT00719836?

The interventions under investigation include: SB1518 (DRUG).

Who is sponsoring clinical trial NCT00719836?

This trial is sponsored by S*BIO, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00719836's enrollment target sits among peer trials

76 705th of 2000 higher than 1,290 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00719836, the US trial registry maintained by the National Library of Medicine. NCT00719836 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.