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NCT00718458 · ClinicalTrials.gov registry record
EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS)
A clinical trial, sponsored by Drexel University College of Medicine.
- Completed
- Registry status
- 102
- Enrollment target
NCT00718458: Completed study, sponsored by Drexel University College of Medicine.
NCT00718458 is a clinical trial that has completed, run by Drexel University College of Medicine. The registered enrollment target is 102 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00718458 has completed, sponsored by Drexel University College of Medicine.
- COMPLETED
- Registry status
- 102 participants
- Enrollment target
Study Summary
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular condition characterized by weakness, muscle wasting, fasciculations and increased reflexes. Depending on the site of onset, individuals with ALS progressively lose control of their skeletal muscles; bulbar or the extremities. As symptoms worsen and spread, muscle atrophy becomes apparent and upper motor neuron symptoms such as spasticity complicate gait (in lower limb involvement) and manual dexterity (in upper limb involvement). The patients progress to a state of profound disability and have great difficulty in communicating; some may even be entirely "locked in" to their bodies. The capacity for simple communication could greatly improve their quality of life. New technologies are giving people with disabilities alternate communication and control options. One such instrument is the EEG-based Brain-Computer Interface (BCI) which can provide both communication and control functions to those who have lost muscle control. By recording electroencephalographic (EEG) signals or brain waves from the scalp and then decoding them, the Wadsworth BCI allows people to make selections on a computer screen \[i\] In this study we will be investigating the feasibility of using EEG-based Brain-Computer Interface technology as a communication solution for individuals with ALS. The specific question addressed will be: Can individuals with ALS use the BCI for communication when they present with extreme loss of neuromuscular control and severe communication impairments? The goal of the project is to determine whether this device is a practical and realistic means for individuals with ALS to communicate. The study is intended to evaluate both the complexity of the system and the degree to which each participant will be able to communicate. Trials will consist of asking the subject to follow a series of simple instructions and complete certain tasks while using the BCI. This study design requires that the individual
Primary Outcome
Measurement of percent spelling accuracy of the BCI system will be a main factor in determining usability of the system.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2007-08 |
| Est. Completion | 2016-12 |
What the finished NCT00718458 record still lists
NCT00718458 is an observational study that tracks outcomes without assigning an intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00718458 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00718458 about?
NCT00718458 is a clinical study titled "EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS)". Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular condition characterized by weakness, muscle wasting, fasciculations and increased reflexes. Depending on the site of onset, individuals with ALS progressively lose control of their skeletal muscles; bulbar or the extremities. As symp...
What is the current status of trial NCT00718458?
This trial is currently completed. The enrollment target is 102 participants. The study started on 2007-08. Estimated completion is 2016-12.
Who is sponsoring clinical trial NCT00718458?
This trial is sponsored by Drexel University College of Medicine, which has 25 total clinical trials registered on ClinicalTrials.gov.
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