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NCT00715273 · ClinicalTrials.gov registry record · Phase 4
Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication
A Phase 4 study, sponsored by University of Washington.
- Completed
- Registry status
- Phase 4
- Development phase
- 217
- Enrollment target
NCT00715273: Completed Phase 4 study, sponsored by University of Washington.
NCT00715273 is a Phase 4 study that has completed, run by University of Washington. The registered enrollment target is 217 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00715273, a Phase 4 study, has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 217 participants
- Enrollment target
Study Summary
Atherosclerosis is a condition that occurs when fatty deposits build up along the inner walls of arteries. This study will examine the effectiveness of a combination of cholesterol-lowering medications at decreasing the fat content of atherosclerotic deposits in people who have coronary artery disease or carotid artery disease.
Primary Outcome
The primary endpoint of this study is carotid plaque lipid composition identified by MRI. The determination of plaque lipid content for each carotid artery will be performed using the automated interactive system. These measurements will be performed from the MRI scans at four time points blinded to time sequence of MRI examinations, patient treatment, lipid levels and clinical course. Volume Measurements: Contours were placed around the lumen, outer-wall boundaries, and plaque features of caro
Interventions
- DRUG Niacin
- DRUG Colesevelam
- DRUG Atorvastatin
- DRUG Placebo Niacin
- DRUG Placebo Colesevelam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 217 participants |
| Start Date | 2001-05-01 |
| Est. Completion | 2019-03-01 |
| Phase | Phase 4 |
What the finished NCT00715273 record still lists
NCT00715273 is an interventional study that assigns participants to a tested intervention. The registered 217 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 5 interventions - of which Niacin is the first listed.
NCT00715273 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00715273 about?
NCT00715273 is a clinical study titled "Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication". Atherosclerosis is a condition that occurs when fatty deposits build up along the inner walls of arteries. This study will examine the effectiveness of a combination of cholesterol-lowering medications at decreasing the fat content of atherosclerotic deposits in people who have coronary artery disea...
What is the current status of trial NCT00715273?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 217 participants. The study started on 2001-05-01. Estimated completion is 2019-03-01.
What interventions are being tested in trial NCT00715273?
The interventions under investigation include: Niacin (DRUG), Colesevelam (DRUG), Atorvastatin (DRUG), Placebo Niacin (DRUG), Placebo Colesevelam (DRUG).
Who is sponsoring clinical trial NCT00715273?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00715273's enrollment target sits among peer trials
217 393rd of 2000 higher than 1,608 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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