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NCT00712855 · ClinicalTrials.gov registry record · Phase 1

A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma

A Phase 1 study, sponsored by Human Genome Sciences Inc., a GSK Company.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT00712855 is a Phase 1 study that has completed, run by Human Genome Sciences Inc., a GSK Company. The registered enrollment target is 23 participants.

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The verdict

NCT00712855, a Phase 1 study, has completed, sponsored by Human Genome Sciences Inc., a GSK Company.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and tolerability of escalating doses of mapatumumab in combination with sorafenib in subjects with advanced Hepatocellular Carcinoma who are positive for hepatitis B surface antigen or hepatitis C antibody.

Interventions

  • DRUG sorafenib
  • BIOLOGICAL mapatumumab

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2008-06
Est. Completion 2012-08
Phase Phase 1

What the Registry Record Tells You About NCT00712855

The ClinicalTrials.gov registry entry for NCT00712855 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Human Genome Sciences Inc., a GSK Company, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which sorafenib is the first listed.

NCT00712855 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00712855 about?

NCT00712855 is a clinical study titled "A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma". The purpose of this study is to evaluate the safety and tolerability of escalating doses of mapatumumab in combination with sorafenib in subjects with advanced Hepatocellular Carcinoma who are positive for hepatitis B surface antigen or hepatitis C antibody.

What is the current status of trial NCT00712855?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2008-06. Estimated completion is 2012-08.

What interventions are being tested in trial NCT00712855?

The interventions under investigation include: sorafenib (DRUG), mapatumumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00712855?

This trial is sponsored by Human Genome Sciences Inc., a GSK Company, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.