Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00702143 · ClinicalTrials.gov registry record · Phase 2

A Phase II Trial of 18F-AV-45 Positron Emission Tomography (PET) Imaging in Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)

A Phase 2 study, sponsored by Avid Radiopharmaceuticals.

Completed
Registry status
Phase 2
Development phase
184
Enrollment target

NCT00702143: Completed Phase 2 study, sponsored by Avid Radiopharmaceuticals.

NCT00702143 is a Phase 2 study that has completed, run by Avid Radiopharmaceuticals. The registered enrollment target is 184 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00702143, a Phase 2 study, has completed, sponsored by Avid Radiopharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
184 participants
Enrollment target

Study Summary

Evaluate 18F-AV-45 positron emission tomography (PET) imaging for distinguishing healthy control subjects, from subjects with Alzheimer's disease (AD) or Mild cognitive impairment (MCI).

Primary Outcome

Three readers blinded to all clinical information classified florbetapir-Positron Emission Tomography (PET) images as either positive for amyloid or negative for amyloid. The majority read was the primary efficacy endpoint for the qualitative evaluation.

Interventions

  • DRUG florbetapir F 18

Trial Details

FieldValue
Enrollment Target 184 participants
Start Date 2008-06
Est. Completion 2008-12
Phase Phase 2
Avid Radiopharmaceuticals

42 total trials

What the finished NCT00702143 record still lists

NCT00702143 is an interventional study that assigns participants to a tested intervention. The registered 184 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% higher).

The record links to 0 conditions, and to 1 intervention - of which florbetapir F 18 is the first listed.

NCT00702143 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00702143 about?

NCT00702143 is a clinical study titled "A Phase II Trial of 18F-AV-45 Positron Emission Tomography (PET) Imaging in Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)". Evaluate 18F-AV-45 positron emission tomography (PET) imaging for distinguishing healthy control subjects, from subjects with Alzheimer's disease (AD) or Mild cognitive impairment (MCI).

What is the current status of trial NCT00702143?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 184 participants. The study started on 2008-06. Estimated completion is 2008-12.

What interventions are being tested in trial NCT00702143?

The interventions under investigation include: florbetapir F 18 (DRUG).

Who is sponsoring clinical trial NCT00702143?

This trial is sponsored by Avid Radiopharmaceuticals, which has 42 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00702143's enrollment target sits among peer trials

184 360th of 2000 higher than 1,638 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03903510 · 184 participants · NA

    Virtual Reality During Pediatric Cast Removal

  • NCT04020510 · 184 participants · Phase 4

    Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

  • NCT04135846 · 184 participants · Phase 2

    Alpha-1 Blockade for Alcohol Use Disorder (AUD)

  • NCT04396873 · 184 participants · Phase 1

    PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00702143, the US trial registry maintained by the National Library of Medicine. NCT00702143 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.