Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00701376 · ClinicalTrials.gov registry record · NA

Hepatic Effects of Gastric Bypass Surgery

A NA study, sponsored by The Cleveland Clinic.

Completed
Registry status
NA
Development phase
106
Enrollment target

NCT00701376: Completed NA study, sponsored by The Cleveland Clinic.

NCT00701376 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 106 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00701376, a NA study, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
NA
Development phase
106 participants
Enrollment target

Study Summary

Liver disease in the morbidly obese is thought to occur due to the long-term presence of fat deposits in the liver, resulting in inflammation and scarring of the liver over time, which reduces liver function. However, many of these patients are unaware that their liver is damaged. There is currently no consensus regarding what the long-term effects of gastric bypass surgery are on pre-existing liver disease in morbidly obese patients. This study will determine the long-term effects on the liver after this type of surgical procedure.

Primary Outcome

To assess the liver function change from before surgery to the time when they lost 60% of their preoperative excess weight or weight loss had plateaued after this procedure (after the procedure minus versus before the procedure)

Interventions

  • OTHER liver biopsy

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2008-06
Est. Completion 2014-09
Phase NA
The Cleveland Clinic

688 total trials

What the finished NCT00701376 record still lists

NCT00701376 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which liver biopsy is the first listed.

NCT00701376 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00701376 about?

NCT00701376 is a clinical study titled "Hepatic Effects of Gastric Bypass Surgery". Liver disease in the morbidly obese is thought to occur due to the long-term presence of fat deposits in the liver, resulting in inflammation and scarring of the liver over time, which reduces liver function. However, many of these patients are unaware that their liver is damaged. There is currently...

What is the current status of trial NCT00701376?

This trial is currently completed. It is a NA study. The enrollment target is 106 participants. The study started on 2008-06. Estimated completion is 2014-09.

What interventions are being tested in trial NCT00701376?

The interventions under investigation include: liver biopsy (OTHER).

Who is sponsoring clinical trial NCT00701376?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00701376's enrollment target sits among peer trials

106 830th of 2000 higher than 1,167 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03181048 · 106 participants · NA

    Clinical Trial of Concomitant Hip Arthroscopy During PAO

  • NCT04682158 · 106 participants · Phase 2

    Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

  • NCT04724018 · 106 participants · Phase 1

    Sacituzumab Govitecan Plus EV in Metastatic UC

  • NCT04798274 · 106 participants · NA

    Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00701376, the US trial registry maintained by the National Library of Medicine. NCT00701376 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.