Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00701181 · ClinicalTrials.gov registry record · Phase 2

Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema

A Phase 2 study, sponsored by Quark Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
184
Enrollment target

NCT00701181: Clinical Trial Phase 2 study, sponsored by Quark Pharmaceuticals.

NCT00701181 is a Phase 2 study that was terminated before completion, run by Quark Pharmaceuticals. The registered enrollment target is 184 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00701181, a Phase 2 study, was terminated before completion, sponsored by Quark Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
184 participants
Enrollment target

Study Summary

To evaluate the effectiveness of study drug in improving visual acuity compared to laser treatment in the patients with diabetic macular edema

Interventions

  • PROCEDURE Laser Treatment
  • DRUG PF-04523655 high
  • DRUG PF-04523655 middle
  • DRUG PF-04523655 low

Trial Details

FieldValue
Enrollment Target 184 participants
Start Date 2008-06
Est. Completion 2011-01
Phase Phase 2
Quark Pharmaceuticals

14 total trials

Why NCT00701181 stopped before completion

NCT00701181 is an interventional study that assigns participants to a tested intervention. The registered 184 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% higher).

The record links to 0 conditions, and to 4 interventions - of which Laser Treatment is the first listed.

NCT00701181 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00701181 about?

NCT00701181 is a clinical study titled "Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema". To evaluate the effectiveness of study drug in improving visual acuity compared to laser treatment in the patients with diabetic macular edema

What is the current status of trial NCT00701181?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 184 participants. The study started on 2008-06. Estimated completion is 2011-01.

What interventions are being tested in trial NCT00701181?

The interventions under investigation include: Laser Treatment (PROCEDURE), PF-04523655 high (DRUG), PF-04523655 middle (DRUG), PF-04523655 low (DRUG).

Who is sponsoring clinical trial NCT00701181?

This trial is sponsored by Quark Pharmaceuticals, which has 14 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00701181's enrollment target sits among peer trials

184 360th of 2000 higher than 1,638 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03903510 · 184 participants · NA

    Virtual Reality During Pediatric Cast Removal

  • NCT04020510 · 184 participants · Phase 4

    Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

  • NCT04135846 · 184 participants · Phase 2

    Alpha-1 Blockade for Alcohol Use Disorder (AUD)

  • NCT04396873 · 184 participants · Phase 1

    PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00701181, the US trial registry maintained by the National Library of Medicine. NCT00701181 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.