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NCT00698776 · ClinicalTrials.gov registry record · Phase 1
Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT00698776: Completed Phase 1 study, sponsored by Yale University.
NCT00698776 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00698776, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
This is a single arm open label trial to test the tolerability of the combination of monocyte derived DCs loaded with KRN7000 (DC-KRN7000) and Lenalidomide (LEN) in patients with asymptomatic myeloma. Phase I component of the study will evaluate the optimal dose of LEN, with particular emphasis on safety. After an interim analysis of these data, a single dose level will be chosen for phase II component in additional patients.
Interventions
- DRUG Lenalidomide
- BIOLOGICAL Monocyte derived DCs loaded with KRN7000
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2009-04 |
| Est. Completion | 2011-05 |
| Phase | Phase 1 |
What the finished NCT00698776 record still lists
NCT00698776 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Lenalidomide is the first listed.
NCT00698776 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00698776 about?
NCT00698776 is a clinical study titled "Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma". This is a single arm open label trial to test the tolerability of the combination of monocyte derived DCs loaded with KRN7000 (DC-KRN7000) and Lenalidomide (LEN) in patients with asymptomatic myeloma. Phase I component of the study will evaluate the optimal dose of LEN, with particular emphasis on s...
What is the current status of trial NCT00698776?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2009-04. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00698776?
The interventions under investigation include: Lenalidomide (DRUG), Monocyte derived DCs loaded with KRN7000 (BIOLOGICAL).
Who is sponsoring clinical trial NCT00698776?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00698776's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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