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NCT00696618 · ClinicalTrials.gov registry record · NA

Enema Use and Acceptability in HIV Negative Men Who Have Sex With Men

A NA study of HIV Infections, sponsored by Johns Hopkins University.

Completed
Registry status
NA
Development phase
9
Enrollment target
1
Study location

NCT00696618: Completed NA study of HIV Infections, sponsored by Johns Hopkins University.

NCT00696618 is a NA study of HIV Infections that has completed, run by Johns Hopkins University. The registered enrollment target is 9 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00696618, a NA study of HIV Infections, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
NA
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

This study is looking at 3 different types of enemas used before receptive anal intercourse in men who have sex with men (MSM). We are investigating whether the enemas cause any damage to the lining of the colon, how far up the colon the enemas travel after they are given, and how much study participants like using each of the enemas.

Primary Outcome

Endoscopy will be performed to obtain biopsy specimens at baseline and following each inpatient enema exposure. Samples will be obtained at each flexible sigmoidoscopy and set aside for batch sectioning and H\&E staining. Slides will be reviewed and scored by a qualified pathologist blinded to treatment assignment using a qualitative scoring system. This scoring system uses semi-quantitative scoring that focuses on acute toxicity to epithelial cell layer similar to that seen in animal studies. T

Conditions Studied

Interventions

  • DRUG Fleet Enema
  • DRUG tap water enema
  • DRUG Normosol-R enema

Study Locations (1)

Maryland

  • Johns Hopkins University - Baltimore

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2007-07
Est. Completion 2012-03
Phase NA
Johns Hopkins University

1,448 total trials

What the finished NCT00696618 record still lists

NCT00696618 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 3 interventions - of which Fleet Enema is the first listed.

NCT00696618 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00696618 about?

NCT00696618 is a clinical study titled "Enema Use and Acceptability in HIV Negative Men Who Have Sex With Men". This study is looking at 3 different types of enemas used before receptive anal intercourse in men who have sex with men (MSM). We are investigating whether the enemas cause any damage to the lining of the colon, how far up the colon the enemas travel after they are given, and how much study partici...

What is the current status of trial NCT00696618?

This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2007-07. Estimated completion is 2012-03.

What conditions does trial NCT00696618 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00696618?

The interventions under investigation include: Fleet Enema (DRUG), tap water enema (DRUG), Normosol-R enema (DRUG).

Who is sponsoring clinical trial NCT00696618?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00696618 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00696618's enrollment target sits among peer trials

9 530th of 542 higher than 11 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00696618, the US trial registry maintained by the National Library of Medicine. NCT00696618 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.