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NCT00684905 · ClinicalTrials.gov registry record · Phase 2
Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT00684905: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT00684905 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00684905, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide and bicalutamide, may lessen the amount of androgens made by the body. Implant radiation therapy kills tumor cells by placing material such as radioactive iodine directly into or near a tumor. Giving leuprolide and bicalutamide together with implant radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects of giving leuprolide and bicalutamide together with implant radiation therapy and to see how well it works in treating patients with locally recurrent prostate cancer after external-beam radiation therapy.
Interventions
- DRUG leuprolide acetate
- PROCEDURE quality-of-life assessment
- PROCEDURE adjuvant therapy
- DRUG bicalutamide
- PROCEDURE neoadjuvant therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2000-04 |
| Est. Completion | 2005-10 |
| Phase | Phase 2 |
What the finished NCT00684905 record still lists
NCT00684905 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 5 interventions - of which leuprolide acetate is the first listed.
NCT00684905 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00684905 about?
NCT00684905 is a clinical study titled "Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy". RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide and bicalutamide, may lessen the amount of androgens made by the body. Implant radiation therapy kills tumor cells by placing material such as radioactive iodine directly into or near a tumor....
What is the current status of trial NCT00684905?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2000-04. Estimated completion is 2005-10.
What interventions are being tested in trial NCT00684905?
The interventions under investigation include: leuprolide acetate (DRUG), quality-of-life assessment (PROCEDURE), adjuvant therapy (PROCEDURE), bicalutamide (DRUG), neoadjuvant therapy (PROCEDURE).
Who is sponsoring clinical trial NCT00684905?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00684905's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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