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NCT00683722 · ClinicalTrials.gov registry record · Phase 2

PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

A Phase 2 study, sponsored by Mesoblast.

Completed
Registry status
Phase 2
Development phase
62
Enrollment target

NCT00683722: Completed Phase 2 study, sponsored by Mesoblast.

NCT00683722 is a Phase 2 study that has completed, run by Mesoblast. The registered enrollment target is 62 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00683722, a Phase 2 study, has completed, sponsored by Mesoblast.

COMPLETED
Registry status
Phase 2
Development phase
62 participants
Enrollment target

Study Summary

The objective of the present study is to establish the safety and efficacy of multiple administrations of Prochymal™(ex-vivo cultured human adult mesenchymal stem cells) in participants with moderate to severe chronic obstructive pulmonary disease (COPD).

Interventions

  • DRUG Placebo
  • DRUG Prochymal™

Trial Details

FieldValue
Enrollment Target 62 participants
Start Date 2008-03-20
Est. Completion 2010-08-24
Phase Phase 2
Mesoblast

25 total trials

What the finished NCT00683722 record still lists

NCT00683722 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00683722 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00683722 about?

NCT00683722 is a clinical study titled "PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)". The objective of the present study is to establish the safety and efficacy of multiple administrations of Prochymal™(ex-vivo cultured human adult mesenchymal stem cells) in participants with moderate to severe chronic obstructive pulmonary disease (COPD).

What is the current status of trial NCT00683722?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 62 participants. The study started on 2008-03-20. Estimated completion is 2010-08-24.

What interventions are being tested in trial NCT00683722?

The interventions under investigation include: Placebo (DRUG), Prochymal™ (DRUG).

Who is sponsoring clinical trial NCT00683722?

This trial is sponsored by Mesoblast, which has 25 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00683722's enrollment target sits among peer trials

62 1016th of 2000 higher than 975 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00683722, the US trial registry maintained by the National Library of Medicine. NCT00683722 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.