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NCT00682357 · ClinicalTrials.gov registry record · NA
Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis
A NA study, sponsored by University of Kansas Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT00682357: Completed NA study, sponsored by University of Kansas Medical Center.
NCT00682357 is a NA study that has completed, run by University of Kansas Medical Center. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00682357, a NA study, has completed, sponsored by University of Kansas Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
Oral and nasal steroids may enhance osteoporosis by suppressing bone formation. Intra-articular steroids may also suppress bone formation, however, the duration or relationship to a steroid dose has not been established. It is hypothesized that intra-articular steroids suppress bone formation transiently, returning to pretreatment levels within four weeks in subjects with osteoarthritis.
Primary Outcome
Change in serum markers of bone formation (osteocalcin) from Day 0 to Day 28.
Interventions
- DRUG Methylprednisolone and Lidocaine
- DRUG Placebo and Lidocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2008-05 |
| Est. Completion | 2010-05 |
| Phase | NA |
What the finished NCT00682357 record still lists
NCT00682357 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Methylprednisolone and Lidocaine is the first listed.
NCT00682357 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00682357 about?
NCT00682357 is a clinical study titled "Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis". Oral and nasal steroids may enhance osteoporosis by suppressing bone formation. Intra-articular steroids may also suppress bone formation, however, the duration or relationship to a steroid dose has not been established. It is hypothesized that intra-articular steroids suppress bone formation transi...
What is the current status of trial NCT00682357?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2008-05. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00682357?
The interventions under investigation include: Methylprednisolone and Lidocaine (DRUG), Placebo and Lidocaine (DRUG).
Who is sponsoring clinical trial NCT00682357?
This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00682357's enrollment target sits among peer trials
25 1712th of 2000 higher than 265 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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