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NCT00669890 · ClinicalTrials.gov registry record · Phase 1

Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML

A Phase 1 study, sponsored by New York Medical College.

Terminated
Registry status
Phase 1
Development phase
12
Enrollment target

NCT00669890 is a Phase 1 study that was terminated before completion, run by New York Medical College. The registered enrollment target is 12 participants.

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The verdict

NCT00669890, a Phase 1 study, was terminated before completion, sponsored by New York Medical College.

TERMINATED
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

The addition of gemtuzumab ozogamicin (GO) in combination with Busulfan/Cyclophosphamide followed by AlloSCT in patients with high risk CD33+ AML/JMML/MDS will be safe and well tolerated. This study will attempt to determine the maximum tolerated dose of the immune therapy (gemtuzumab) when given in combination with the myeloablative (high dose) drugs used in this study for allogeneic stem cell transplant. (Part A)

Interventions

  • DRUG Cyclophosphamide
  • DRUG Busulfan
  • DRUG Gemtuzumab Ozogamicin
  • DRUG Thymoglobulin
  • DRUG Tacrolimus

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2004-05
Est. Completion 2013-12
Phase Phase 1

Sponsor

New York Medical College

47 total trials

What the Registry Record Tells You About NCT00669890

The ClinicalTrials.gov registry entry for NCT00669890 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is New York Medical College, which has 47 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT00669890 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00669890 about?

NCT00669890 is a clinical study titled "Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML". The addition of gemtuzumab ozogamicin (GO) in combination with Busulfan/Cyclophosphamide followed by AlloSCT in patients with high risk CD33+ AML/JMML/MDS will be safe and well tolerated. This study will attempt to determine the maximum tolerated dose of the immune therapy (gemtuzumab) when given i...

What is the current status of trial NCT00669890?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2004-05. Estimated completion is 2013-12.

What interventions are being tested in trial NCT00669890?

The interventions under investigation include: Cyclophosphamide (DRUG), Busulfan (DRUG), Gemtuzumab Ozogamicin (DRUG), Thymoglobulin (DRUG), Tacrolimus (DRUG).

Who is sponsoring clinical trial NCT00669890?

This trial is sponsored by New York Medical College, which has 47 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.