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NCT00667420 · ClinicalTrials.gov registry record · Phase 1

Perioperative Panitumumab and Epirubicin, Oxaliplatin and Xeloda (EOX) in Patients With Gastroesophageal Adenocarcinoma

A Phase 1 study, sponsored by Massachusetts General Hospital.

Terminated
Registry status
Phase 1
Development phase
17
Enrollment target

NCT00667420: Clinical Trial Phase 1 study, sponsored by Massachusetts General Hospital.

NCT00667420 is a Phase 1 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 17 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00667420, a Phase 1 study, was terminated before completion, sponsored by Massachusetts General Hospital.

TERMINATED
Registry status
Phase 1
Development phase
17 participants
Enrollment target

Study Summary

A pilot study to determine the safety of using perioperative panitumumab with EOX (epirubicin, oxaliplatin, and capecitabine) in patients with adenocarcinoma of the esophagus and stomach.

Primary Outcome

Safety and tolerability were measured by assessing the number of participants able to complete 3 cycles of pre-operative chemotherapy

Interventions

  • DRUG panitumumab, epirubicin, oxaliplatin, xeloda

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2008-04
Est. Completion 2014-06
Phase Phase 1
Massachusetts General Hospital

2,032 total trials

Why NCT00667420 stopped before completion

NCT00667420 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower).

The record links to 0 conditions, and to 1 intervention - of which panitumumab, epirubicin, oxaliplatin, xeloda is the first listed.

NCT00667420 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00667420 about?

NCT00667420 is a clinical study titled "Perioperative Panitumumab and Epirubicin, Oxaliplatin and Xeloda (EOX) in Patients With Gastroesophageal Adenocarcinoma". A pilot study to determine the safety of using perioperative panitumumab with EOX (epirubicin, oxaliplatin, and capecitabine) in patients with adenocarcinoma of the esophagus and stomach.

What is the current status of trial NCT00667420?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2008-04. Estimated completion is 2014-06.

What interventions are being tested in trial NCT00667420?

The interventions under investigation include: panitumumab, epirubicin, oxaliplatin, xeloda (DRUG).

Who is sponsoring clinical trial NCT00667420?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00667420's enrollment target sits among peer trials

17 1785th of 2000 higher than 215 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00667420, the US trial registry maintained by the National Library of Medicine. NCT00667420 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.