Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00658957 · ClinicalTrials.gov registry record · Phase 2

Prevention of Infection Using a Topical Gentamicin-Collagen Sponge in Diabetic Patients With An Uninfected Foot Ulcer

A Phase 2 study, sponsored by Innocoll.

Terminated
Registry status
Phase 2
Development phase
49
Enrollment target

NCT00658957: Clinical Trial Phase 2 study, sponsored by Innocoll.

NCT00658957 is a Phase 2 study that was terminated before completion, run by Innocoll. The registered enrollment target is 49 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00658957, a Phase 2 study, was terminated before completion, sponsored by Innocoll.

TERMINATED
Registry status
Phase 2
Development phase
49 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and efficacy of the topical gentamicin collagen sponge (gentamicin sponge) combined with standard of care (daily wound care, off-loading, diabetic control and debridement by a physician or podiatrist), compared with placebo sponge combined with standard of care, in preventing infection of diabetic lower extremity skin ulcers.

Interventions

  • DRUG placebo collagen sponge
  • DRUG gentamicin-collagen sponge

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2008-04
Est. Completion 2009-10
Phase Phase 2
Innocoll

19 total trials

Why NCT00658957 stopped before completion

NCT00658957 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo collagen sponge is the first listed.

NCT00658957 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00658957 about?

NCT00658957 is a clinical study titled "Prevention of Infection Using a Topical Gentamicin-Collagen Sponge in Diabetic Patients With An Uninfected Foot Ulcer". The purpose of this study is to determine the safety and efficacy of the topical gentamicin collagen sponge (gentamicin sponge) combined with standard of care (daily wound care, off-loading, diabetic control and debridement by a physician or podiatrist), compared with placebo sponge combined with st...

What is the current status of trial NCT00658957?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 49 participants. The study started on 2008-04. Estimated completion is 2009-10.

What interventions are being tested in trial NCT00658957?

The interventions under investigation include: placebo collagen sponge (DRUG), gentamicin-collagen sponge (DRUG).

Who is sponsoring clinical trial NCT00658957?

This trial is sponsored by Innocoll, which has 19 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00658957's enrollment target sits among peer trials

49 1261st of 2000 higher than 736 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02704858 · 49 participants · Phase 1

    Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

  • NCT03516708 · 49 participants · Phase 1

    Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

  • NCT03692429 · 49 participants · Phase 1

    alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells

  • NCT04329494 · 49 participants · Phase 1

    PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00658957, the US trial registry maintained by the National Library of Medicine. NCT00658957 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.