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NCT00656487 · ClinicalTrials.gov registry record · Phase 2
Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults
A Phase 2 study, sponsored by The Scripps Research Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 66
- Enrollment target
NCT00656487: Completed Phase 2 study, sponsored by The Scripps Research Institute.
NCT00656487 is a Phase 2 study that has completed, run by The Scripps Research Institute. The registered enrollment target is 66 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00656487, a Phase 2 study, has completed, sponsored by The Scripps Research Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 66 participants
- Enrollment target
Study Summary
The purpose of this study is to find out more about cognitive functioning in people who are cannabis dependent, relative to people who do not use cannabis, and how their brains process information after one month of not using cannabis. An additional goal is to characterize the severity of cannabis dependence using precipitated and naturalistic withdrawal with a double blind, placebo controlled, single administration of rimonabant. Research assessments occur bi-weekly throughout this 28 day study.
Primary Outcome
The MWC is a 28-item instrument that is used to assess the severity of frequently reported cannabis withdrawal symptoms. Each item on the measure is recorded as a severity rating between 0-3 where a zero indicates not present and a three indicates severe. The severity rating of each item was summed to obtain a single marijuana withdrawal severity score ranging between 0- 84. A lower score indicates less severe withdrawal.
Interventions
- DRUG placebo
- DRUG rimonabant
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2008-04-30 |
| Est. Completion | 2011-01-06 |
| Phase | Phase 2 |
What the finished NCT00656487 record still lists
NCT00656487 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT00656487 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00656487 about?
NCT00656487 is a clinical study titled "Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults". The purpose of this study is to find out more about cognitive functioning in people who are cannabis dependent, relative to people who do not use cannabis, and how their brains process information after one month of not using cannabis. An additional goal is to characterize the severity of cannabis d...
What is the current status of trial NCT00656487?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2008-04-30. Estimated completion is 2011-01-06.
What interventions are being tested in trial NCT00656487?
The interventions under investigation include: placebo (DRUG), rimonabant (DRUG).
Who is sponsoring clinical trial NCT00656487?
This trial is sponsored by The Scripps Research Institute, which has 16 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00656487's enrollment target sits among peer trials
66 975th of 2000 higher than 1,014 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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