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NCT00646776 · ClinicalTrials.gov registry record · Phase 1
Drug Interaction Study
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 85
- Enrollment target
NCT00646776: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT00646776 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 85 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00646776, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 85 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the exposure of rifabutin (RIB) when administered with atazanavir and ritonavir (ATV/RTV)
Primary Outcome
AUC24avg is AUC(0-24 hour) following dosing on Day 10 for RIB 150mg once daily (QD); AUC24avg is the area under the plasma concentration-time curve in 1 dosing interval (AUC\[TAU\]) divided by the number of days over the sampling duration for ATV/RTV 300/100 mg QD+RIB 150 mg twice weekly, i.e. AUC(TAU)/7.
Interventions
- DRUG Rifabutin
- DRUG Rifabutin + Atazanavir + Ritonavir
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 85 participants |
| Start Date | 2008-04 |
| Est. Completion | 2008-08 |
| Phase | Phase 1 |
What the finished NCT00646776 record still lists
NCT00646776 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher).
The record links to 0 conditions, and to 2 interventions - of which Rifabutin is the first listed.
NCT00646776 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00646776 about?
NCT00646776 is a clinical study titled "Drug Interaction Study". The purpose of this study is to evaluate the exposure of rifabutin (RIB) when administered with atazanavir and ritonavir (ATV/RTV)
What is the current status of trial NCT00646776?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2008-04. Estimated completion is 2008-08.
What interventions are being tested in trial NCT00646776?
The interventions under investigation include: Rifabutin (DRUG), Rifabutin + Atazanavir + Ritonavir (DRUG).
Who is sponsoring clinical trial NCT00646776?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00646776's enrollment target sits among peer trials
85 656th of 2000 higher than 1,342 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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