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NCT00645658 · ClinicalTrials.gov registry record · NA
Testosterone Replacement Therapy in Advanced Chronic Kidney Disease
A NA study, sponsored by Palo Alto Veterans Institute for Research.
- Completed
- Registry status
- NA
- Development phase
- 17
- Enrollment target
NCT00645658: Completed NA study, sponsored by Palo Alto Veterans Institute for Research.
NCT00645658 is a NA study that has completed, run by Palo Alto Veterans Institute for Research. The registered enrollment target is 17 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00645658, a NA study, has completed, sponsored by Palo Alto Veterans Institute for Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 17 participants
- Enrollment target
Study Summary
Muscle wasting is common in advanced chronic kidney disease (CKD) and adversely affects morbidity and mortality. In 2/3 of males with advanced CKD serum testosterone (TT) levels are reduced, and likely contributes to the wasting. As TT in relatively safe physiologic replacement doses, increases muscle mass in otherwise normal TT deficient subjects, we hypothesize that physiologic TT replacement will be effective in preventing and treating the loss of muscle mass and function in CKD patients, will improve quality of life and may reduce some cardiovascular disease (CVD) risk factors.
Primary Outcome
DEXA-determined thigh cross-sectional area
Interventions
- DRUG Testim, 1% testosterone gel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2007-08 |
| Est. Completion | 2010-08 |
| Phase | NA |
What the finished NCT00645658 record still lists
NCT00645658 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Testim, 1% testosterone gel is the first listed.
NCT00645658 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00645658 about?
NCT00645658 is a clinical study titled "Testosterone Replacement Therapy in Advanced Chronic Kidney Disease". Muscle wasting is common in advanced chronic kidney disease (CKD) and adversely affects morbidity and mortality. In 2/3 of males with advanced CKD serum testosterone (TT) levels are reduced, and likely contributes to the wasting. As TT in relatively safe physiologic replacement doses, increases musc...
What is the current status of trial NCT00645658?
This trial is currently completed. It is a NA study. The enrollment target is 17 participants. The study started on 2007-08. Estimated completion is 2010-08.
What interventions are being tested in trial NCT00645658?
The interventions under investigation include: Testim, 1% testosterone gel (DRUG).
Who is sponsoring clinical trial NCT00645658?
This trial is sponsored by Palo Alto Veterans Institute for Research, which has 35 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00645658's enrollment target sits among peer trials
17 1871st of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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