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NCT00643669 · ClinicalTrials.gov registry record · Phase 2

24 Hour IOP Lowering Efficacy of AL-3789

A Phase 2 study, sponsored by Alcon Research.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target

NCT00643669: Completed Phase 2 study, sponsored by Alcon Research.

NCT00643669 is a Phase 2 study that has completed, run by Alcon Research. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00643669, a Phase 2 study, has completed, sponsored by Alcon Research.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target

Study Summary

The objective of this study was to describe the intraocular pressure-lowering efficacy of AL-3789 over a 24-hour period in patients with open-angle glaucoma compared to an untreated control. Patients received one treatment of AL-3789. Twenty-eight days after treatment, IOP was measured every 4 hours, beginning at 8 AM for 24 hours.

Interventions

  • DRUG AL-3789 Sterile Suspension

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2008-02
Phase Phase 2
Alcon Research

275 total trials

What the finished NCT00643669 record still lists

NCT00643669 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 1 intervention - of which AL-3789 Sterile Suspension is the first listed.

NCT00643669 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00643669 about?

NCT00643669 is a clinical study titled "24 Hour IOP Lowering Efficacy of AL-3789". The objective of this study was to describe the intraocular pressure-lowering efficacy of AL-3789 over a 24-hour period in patients with open-angle glaucoma compared to an untreated control. Patients received one treatment of AL-3789. Twenty-eight days after treatment, IOP was measured every 4 hours...

What is the current status of trial NCT00643669?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2008-02.

What interventions are being tested in trial NCT00643669?

The interventions under investigation include: AL-3789 Sterile Suspension (DRUG).

Who is sponsoring clinical trial NCT00643669?

This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00643669's enrollment target sits among peer trials

25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00643669, the US trial registry maintained by the National Library of Medicine. NCT00643669 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.