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NCT00636545 · ClinicalTrials.gov registry record · Phase 1

Genasense as a 2-hour Intravenous Infusion in Subjects With Solid Tumors

A Phase 1 study, sponsored by Genta Incorporated.

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT00636545: Completed Phase 1 study, sponsored by Genta Incorporated.

NCT00636545 is a Phase 1 study that has completed, run by Genta Incorporated. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00636545, a Phase 1 study, has completed, sponsored by Genta Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

The primary objective is to determine the safety and maximum tolerated dose (MTD) of Genasense administered as a 2-hour intravenous infusion once weekly (Part 1) and twice weekly (Part 2) to patients with solid tumors.

Interventions

  • DRUG Oblimersen (Genasense)

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2007-05
Est. Completion 2010-03
Phase Phase 1
Genta Incorporated

12 total trials

What the finished NCT00636545 record still lists

NCT00636545 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 1 intervention - of which Oblimersen (Genasense) is the first listed.

NCT00636545 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00636545 about?

NCT00636545 is a clinical study titled "Genasense as a 2-hour Intravenous Infusion in Subjects With Solid Tumors". The primary objective is to determine the safety and maximum tolerated dose (MTD) of Genasense administered as a 2-hour intravenous infusion once weekly (Part 1) and twice weekly (Part 2) to patients with solid tumors.

What is the current status of trial NCT00636545?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2007-05. Estimated completion is 2010-03.

What interventions are being tested in trial NCT00636545?

The interventions under investigation include: Oblimersen (Genasense) (DRUG).

Who is sponsoring clinical trial NCT00636545?

This trial is sponsored by Genta Incorporated, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00636545's enrollment target sits among peer trials

25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00636545, the US trial registry maintained by the National Library of Medicine. NCT00636545 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.