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NCT00636077 · ClinicalTrials.gov registry record · NA

Comparative Effects Of Dialysate Flow Rate And Membrane Packing On The Performance Of Dialyzers Used For Hemodialysis

A NA study, sponsored by Vantive Health.

Completed
Registry status
NA
Development phase
12
Enrollment target

NCT00636077: Completed NA study, sponsored by Vantive Health.

NCT00636077 is a NA study that has completed, run by Vantive Health. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00636077, a NA study, has completed, sponsored by Vantive Health.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target

Study Summary

The purposes of this study are to determine if the performance of a dialyzer depends on how tightly the hollow fiber membranes are packed in the housing of the dialyzer (the membrane packing density) and if that dependence is a function of the dialysate flow rate. The study will examine how efficiently three different sized molecules pass through a dialyzer membrane at different dialysate flow rates in dialyzers with different membrane packing densities. Transfer of urea, phosphorus and beta-2-microglobulin from blood to dialysate will be measured during clinical hemodialysis using four different dialyzers, each used at three different dialysate flow rates. The data derived from these measurements may provide insight into the importance of membrane packing density as a design parameter for hemodialyzers and if changing the membrane packing density might provide equivalent performance at a lower dialysate flow rate.

Primary Outcome

KoA is a constant that describes the efficiency of a dialyzer in removing urea. KoA is determined by surface area of the membrane, the thickness of the membrane and pore size.

Interventions

  • DEVICE Polyflux HD-C4 Big
  • DEVICE HD-C4 Small
  • DEVICE Optiflux 160NR
  • DEVICE Optiflux 200NR

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2008-02
Est. Completion 2008-04
Phase NA
Vantive Health

15 total trials

What the finished NCT00636077 record still lists

NCT00636077 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 4 interventions - of which Polyflux HD-C4 Big is the first listed.

NCT00636077 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00636077 about?

NCT00636077 is a clinical study titled "Comparative Effects Of Dialysate Flow Rate And Membrane Packing On The Performance Of Dialyzers Used For Hemodialysis". The purposes of this study are to determine if the performance of a dialyzer depends on how tightly the hollow fiber membranes are packed in the housing of the dialyzer (the membrane packing density) and if that dependence is a function of the dialysate flow rate. The study will examine how efficien...

What is the current status of trial NCT00636077?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2008-02. Estimated completion is 2008-04.

What interventions are being tested in trial NCT00636077?

The interventions under investigation include: Polyflux HD-C4 Big (DEVICE), HD-C4 Small (DEVICE), Optiflux 160NR (DEVICE), Optiflux 200NR (DEVICE).

Who is sponsoring clinical trial NCT00636077?

This trial is sponsored by Vantive Health, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00636077's enrollment target sits among peer trials

12 1913th of 2000 higher than 74 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00636077, the US trial registry maintained by the National Library of Medicine. NCT00636077 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.