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NCT00630396 · ClinicalTrials.gov registry record · Phase 1
Study of a Neuroprotective Drug to Limit the Extent of Damage From an Ischemic Stroke
A Phase 1 study of Stroke, Acute, sponsored by David Hess, MD.
- Completed
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 2
- Study locations
NCT00630396: Completed Phase 1 study of Stroke, Acute, sponsored by David Hess, MD.
NCT00630396 is a Phase 1 study of Stroke, Acute that has completed, run by David Hess, MD. The registered enrollment target is 60 participants, below the 628-participant average among 25 other Stroke, Acute trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00630396, a Phase 1 study of Stroke, Acute, has completed, sponsored by David Hess, MD.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 2
- Study locations
Study Summary
The primary aim of this study is to find out which of 4 different doses of minocycline are safe and well tolerated so that we will know the optimal dose to test in future patients.
Primary Outcome
Investigators closely monitored each subject for evidence of minocycline intolerance. All adverse events were immediately reported for a decision whether to discontinue the study medication and/or reduce the dose. A computer program was used to determine the maximum tolerated dose. After entering information regarding doses and expected toxicities, results for each subject as they were collected were entered. The computer program informed as to (de)escalation, or maintenance of the same dose in
Conditions Studied
Interventions
- DRUG Minocycline
Study Locations (2)
Kentucky
- University of Kentucky - Lexington
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2008-05 |
| Est. Completion | 2010-01 |
| Phase | Phase 1 |
What the finished NCT00630396 record still lists
NCT00630396 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 628-participant average among 25 other Stroke, Acute trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Stroke, Acute appearing as the primary indexed condition, and to 1 intervention - of which Minocycline is the first listed.
NCT00630396 reports a single indexed study location in Kentucky, Oregon.
Frequently Asked Questions
What is clinical trial NCT00630396 about?
NCT00630396 is a clinical study titled "Study of a Neuroprotective Drug to Limit the Extent of Damage From an Ischemic Stroke". The primary aim of this study is to find out which of 4 different doses of minocycline are safe and well tolerated so that we will know the optimal dose to test in future patients.
What is the current status of trial NCT00630396?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2008-05. Estimated completion is 2010-01.
What conditions does trial NCT00630396 study?
This clinical trial studies the following conditions: Stroke, Acute.
What interventions are being tested in trial NCT00630396?
The interventions under investigation include: Minocycline (DRUG).
Who is sponsoring clinical trial NCT00630396?
This trial is sponsored by David Hess, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00630396 being conducted?
This trial has 2 study locations across Kentucky, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke, Acute
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00630396's enrollment target sits among peer trials
60 23rd of 25 higher than 3 of 25 other Stroke, Acute trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke, Acute trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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