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NCT00624442 · ClinicalTrials.gov registry record · Phase 2
A Study of CK-1827452 Infusion in Stable Heart Failure
A Phase 2 study, sponsored by Cytokinetics.
- Completed
- Registry status
- Phase 2
- Development phase
- 45
- Enrollment target
NCT00624442: Completed Phase 2 study, sponsored by Cytokinetics.
NCT00624442 is a Phase 2 study that has completed, run by Cytokinetics. The registered enrollment target is 45 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00624442, a Phase 2 study, has completed, sponsored by Cytokinetics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 45 participants
- Enrollment target
Study Summary
This study will assess the safety, tolerability, and pharmacodynamics of CK-1827452 infusion in patients with stable heart failure.
Primary Outcome
Pooled analysis of the echocardiographic measure systolic ejection time from echocardiograms taken at all timepoints. The systolic ejection time is the period during which the aortic valve is open and blood is flowing across the valve. Echocardiograms from cohorts 1,2,3,4 and 5 (564 echocardiograms) were binned into either placebo group or 1 of 6 groups based on plasma concentration of CK-1827452.
Interventions
- DRUG CK-1827452
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2007-04 |
| Est. Completion | 2009-02 |
| Phase | Phase 2 |
What the finished NCT00624442 record still lists
NCT00624442 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% lower).
The record links to 0 conditions, and to 1 intervention - of which CK-1827452 is the first listed.
NCT00624442 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00624442 about?
NCT00624442 is a clinical study titled "A Study of CK-1827452 Infusion in Stable Heart Failure". This study will assess the safety, tolerability, and pharmacodynamics of CK-1827452 infusion in patients with stable heart failure.
What is the current status of trial NCT00624442?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2007-04. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00624442?
The interventions under investigation include: CK-1827452 (DRUG).
Who is sponsoring clinical trial NCT00624442?
This trial is sponsored by Cytokinetics, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00624442's enrollment target sits among peer trials
45 1296th of 2000 higher than 679 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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