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NCT00615212 · ClinicalTrials.gov registry record · Phase 1
Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT00615212: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00615212 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00615212, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
This study is meant to assess potential inhibitory effects of GSK376501 on CYP450 isoenzymes 3A4, 2C8, 2C9. subjects will receive probe compounds and systemic levels of these substrates will be compared pre and post dosing of GSK376501.
Interventions
- DRUG Midazolam
- DRUG Rosiglitazone
- DRUG Flurbiprofen
- DRUG GSK376501
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2008-01-02 |
| Est. Completion | 2008-02-15 |
| Phase | Phase 1 |
What the finished NCT00615212 record still lists
NCT00615212 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 4 interventions - of which Midazolam is the first listed.
NCT00615212 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00615212 about?
NCT00615212 is a clinical study titled "Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects". This study is meant to assess potential inhibitory effects of GSK376501 on CYP450 isoenzymes 3A4, 2C8, 2C9. subjects will receive probe compounds and systemic levels of these substrates will be compared pre and post dosing of GSK376501.
What is the current status of trial NCT00615212?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2008-01-02. Estimated completion is 2008-02-15.
What interventions are being tested in trial NCT00615212?
The interventions under investigation include: Midazolam (DRUG), Rosiglitazone (DRUG), Flurbiprofen (DRUG), GSK376501 (DRUG).
Who is sponsoring clinical trial NCT00615212?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00615212's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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