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NCT00615212 · ClinicalTrials.gov registry record · Phase 1

Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects

A Phase 1 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT00615212 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 23 participants.

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The verdict

NCT00615212, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

This study is meant to assess potential inhibitory effects of GSK376501 on CYP450 isoenzymes 3A4, 2C8, 2C9. subjects will receive probe compounds and systemic levels of these substrates will be compared pre and post dosing of GSK376501.

Interventions

  • DRUG Midazolam
  • DRUG Rosiglitazone
  • DRUG Flurbiprofen
  • DRUG GSK376501

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2008-01-02
Est. Completion 2008-02-15
Phase Phase 1

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT00615212

The ClinicalTrials.gov registry entry for NCT00615212 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Midazolam is the first listed.

NCT00615212 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00615212 about?

NCT00615212 is a clinical study titled "Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects". This study is meant to assess potential inhibitory effects of GSK376501 on CYP450 isoenzymes 3A4, 2C8, 2C9. subjects will receive probe compounds and systemic levels of these substrates will be compared pre and post dosing of GSK376501.

What is the current status of trial NCT00615212?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2008-01-02. Estimated completion is 2008-02-15.

What interventions are being tested in trial NCT00615212?

The interventions under investigation include: Midazolam (DRUG), Rosiglitazone (DRUG), Flurbiprofen (DRUG), GSK376501 (DRUG).

Who is sponsoring clinical trial NCT00615212?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.