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NCT00613015 · ClinicalTrials.gov registry record · Phase 2
Stress and Medication Effects on Cocaine Cue Reactivity
A Phase 2 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 109
- Enrollment target
NCT00613015: Completed Phase 2 study, sponsored by Medical University of South Carolina.
NCT00613015 is a Phase 2 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 109 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00613015, a Phase 2 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 109 participants
- Enrollment target
Study Summary
Stressful situations and cues associated with cocaine can lead to craving in cocaine dependent individuals. The purpose of this study is to determine whether guanfacine or modafinil are effective in reducing stress and cue induced craving in cocaine dependent individuals.
Primary Outcome
Participants were randomized to the modafinil, guanfacine, or placebo treatment group. Participants were then randomized to participate in the TRIER social stress task or to read magazines for 15 minutes. Following the task, participants were exposed to neutral cues for 2 minutes and cocaine cues for 2 minutes. Immediately following the cocaine cue exposure, participants were asked to rate cocaine craving on a 10-point Likert scale, with 0 being Not at All and 10 being Extremely.
Interventions
- DRUG Placebo
- DRUG Modafinil
- DRUG Guanfacine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 109 participants |
| Start Date | 2008-05 |
| Est. Completion | 2012-07 |
| Phase | Phase 2 |
What the finished NCT00613015 record still lists
NCT00613015 is an interventional study that assigns participants to a tested intervention. The registered 109 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (18% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00613015 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00613015 about?
NCT00613015 is a clinical study titled "Stress and Medication Effects on Cocaine Cue Reactivity". Stressful situations and cues associated with cocaine can lead to craving in cocaine dependent individuals. The purpose of this study is to determine whether guanfacine or modafinil are effective in reducing stress and cue induced craving in cocaine dependent individuals.
What is the current status of trial NCT00613015?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 109 participants. The study started on 2008-05. Estimated completion is 2012-07.
What interventions are being tested in trial NCT00613015?
The interventions under investigation include: Placebo (DRUG), Modafinil (DRUG), Guanfacine (DRUG).
Who is sponsoring clinical trial NCT00613015?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00613015's enrollment target sits among peer trials
109 640th of 2000 higher than 1,361 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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