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NCT00612716 · ClinicalTrials.gov registry record · Phase 2

Donor Stem Cell Transplant in Treating Patients With Previously Treated Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

A Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

Completed
Registry status
Phase 2
Development phase
6
Enrollment target

NCT00612716 is a Phase 2 study that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 6 participants.

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The verdict

NCT00612716, a Phase 2 study, has completed, sponsored by Masonic Cancer Center, University of Minnesota.

COMPLETED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

RATIONALE: Giving chemotherapy, such as cyclophosphamide and busulfan, and total-body irradiation before a donor stem cell transplant helps stop the growth of cancer cells. It also stops the patient's immune system from rejecting the donor's stem cells. The donated stem cells from bone marrow or umbilical cord blood may replace the patient's immune cells and help destroy any remaining cancer cells (graft-versus-tumor effect). Sometimes the transplanted cells from a donor can also make an immune response against the body's normal cells. Giving methotrexate and cyclosporine after transplant may stop this from happening. PURPOSE: This phase II trial is studying how well a donor stem cell transplant works in treating patients with previously treated lymphoma, multiple myeloma, or chronic lymphocytic leukemia.

Interventions

  • RADIATION Total body irradiation
  • DRUG cyclophosphamide
  • DRUG busulfan
  • BIOLOGICAL Stem cell infusion

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 1999-10-06
Est. Completion 2019-12-15
Phase Phase 2

What the Registry Record Tells You About NCT00612716

The ClinicalTrials.gov registry entry for NCT00612716 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Total body irradiation is the first listed.

NCT00612716 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00612716 about?

NCT00612716 is a clinical study titled "Donor Stem Cell Transplant in Treating Patients With Previously Treated Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia". RATIONALE: Giving chemotherapy, such as cyclophosphamide and busulfan, and total-body irradiation before a donor stem cell transplant helps stop the growth of cancer cells. It also stops the patient's immune system from rejecting the donor's stem cells. The donated stem cells from bone marrow or umb...

What is the current status of trial NCT00612716?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 1999-10-06. Estimated completion is 2019-12-15.

What interventions are being tested in trial NCT00612716?

The interventions under investigation include: Total body irradiation (RADIATION), cyclophosphamide (DRUG), busulfan (DRUG), Stem cell infusion (BIOLOGICAL).

Who is sponsoring clinical trial NCT00612716?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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