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NCT00604461 · ClinicalTrials.gov registry record · Phase 1

Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With Malignant Pleural Mesothelioma (MPM)

A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Terminated
Registry status
Phase 1
Development phase
13
Enrollment target

NCT00604461 is a Phase 1 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 13 participants.

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The verdict

NCT00604461, a Phase 1 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

TERMINATED
Registry status
Phase 1
Development phase
13 participants
Enrollment target

Study Summary

The purpose of this research study was to evaluate how effective the combination of Carboplatin, Bevacizumab (Avastin™) and, Pemetrexed (Alimta™) is in the treatment of patients with Malignant Pleural Mesothelioma (MPM). A combination of cisplatin and pemetrexed is considered standard for this disease and typically off protocol patients would receive cisplatin or carboplatin and pemetrexed as standard of care. The planned length of the study (first patient screened to last patient enrolled) was 24 months. The planned length of the entire study (enrollment period + the treatment period + a follow-up period of at least 12 months) was 36 months.

Interventions

  • DRUG Carboplatin, Bevacizumab and Pemetrexed

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2007-10
Est. Completion 2011-01
Phase Phase 1

What the Registry Record Tells You About NCT00604461

The ClinicalTrials.gov registry entry for NCT00604461 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Carboplatin, Bevacizumab and Pemetrexed is the first listed.

NCT00604461 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00604461 about?

NCT00604461 is a clinical study titled "Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With Malignant Pleural Mesothelioma (MPM)". The purpose of this research study was to evaluate how effective the combination of Carboplatin, Bevacizumab (Avastin™) and, Pemetrexed (Alimta™) is in the treatment of patients with Malignant Pleural Mesothelioma (MPM). A combination of cisplatin and pemetrexed is considered standard for this disea...

What is the current status of trial NCT00604461?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2007-10. Estimated completion is 2011-01.

What interventions are being tested in trial NCT00604461?

The interventions under investigation include: Carboplatin, Bevacizumab and Pemetrexed (DRUG).

Who is sponsoring clinical trial NCT00604461?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.