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NCT00603577 · ClinicalTrials.gov registry record · Phase 3

Role of Xaliproden on Recovery Rate From Severe Neuropathy in Patients Who Have Completed Adjuvant Chemotherapy With Oxaliplatin Based Regimens

A Phase 3 study, sponsored by Sanofi.

Terminated
Registry status
Phase 3
Development phase
102
Enrollment target

NCT00603577 is a Phase 3 study that was terminated before completion, run by Sanofi. The registered enrollment target is 102 participants.

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The verdict

NCT00603577, a Phase 3 study, was terminated before completion, sponsored by Sanofi.

TERMINATED
Registry status
Phase 3
Development phase
102 participants
Enrollment target

Study Summary

Primary objective: To assess the effect of xaliproden hydrochloride (xaliproden) 1 mg per oral daily on the rate of complete resolution of peripheral sensory neuropathy (PSN) at 6 months, following randomization, after the completion of oxaliplatin-based adjuvant chemotherapy for colon cancer. Secondary objective: * To assess the effect of xaliproden on patient-reported outcomes using the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity scale (FACT/GOG NTX-12 subscale). * To assess the effect of xaliproden on the rate of at least partial recovery of grade \> 2 PSN at 6 months * To assess the effects of xaliproden on the time to complete recovery from PSN * To evaluate the safety profile of xaliproden

Interventions

  • DRUG Placebo
  • DRUG Xaliproden

Trial Details

FieldValue
Enrollment Target 102 participants
Start Date 2008-01
Est. Completion 2009-11
Phase Phase 3

Sponsor

Sanofi

713 total trials

What the Registry Record Tells You About NCT00603577

The ClinicalTrials.gov registry entry for NCT00603577 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00603577 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00603577 about?

NCT00603577 is a clinical study titled "Role of Xaliproden on Recovery Rate From Severe Neuropathy in Patients Who Have Completed Adjuvant Chemotherapy With Oxaliplatin Based Regimens". Primary objective: To assess the effect of xaliproden hydrochloride (xaliproden) 1 mg per oral daily on the rate of complete resolution of peripheral sensory neuropathy (PSN) at 6 months, following randomization, after the completion of oxaliplatin-based adjuvant chemotherapy for colon cancer. Sec...

What is the current status of trial NCT00603577?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 102 participants. The study started on 2008-01. Estimated completion is 2009-11.

What interventions are being tested in trial NCT00603577?

The interventions under investigation include: Placebo (DRUG), Xaliproden (DRUG).

Who is sponsoring clinical trial NCT00603577?

This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.