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NCT00603044 · ClinicalTrials.gov registry record · Phase 4
Mechanism of Action of Fluticasone Furoate in Childhood Obstructive Sleep Apnea Syndrome
A Phase 4 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
NCT00603044: Completed Phase 4 study, sponsored by University of Chicago.
NCT00603044 is a Phase 4 study that has completed, run by University of Chicago. The registered enrollment target is 24 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00603044, a Phase 4 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this research is to find out how a nasal spray (fluticasone furoate), sometimes given to children with obstructive sleep apnea syndrome (OSAS), works on certain cells within a child's adenoids. We hypothesize that intranasal steroids lead to an upregulation of T regulatory cells in the adenoid tissues of children with OSAS. This will result in a local reduction in inflammation and edema explaining the improvement in OSAS.
Primary Outcome
The number of tissue T-regulatory cells, as determined by staining with FOXP3, CD4, and CD25
Interventions
- DRUG fluticasone furoate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2008-01 |
| Est. Completion | 2009-08 |
| Phase | Phase 4 |
What the finished NCT00603044 record still lists
NCT00603044 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which fluticasone furoate is the first listed.
NCT00603044 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00603044 about?
NCT00603044 is a clinical study titled "Mechanism of Action of Fluticasone Furoate in Childhood Obstructive Sleep Apnea Syndrome". The purpose of this research is to find out how a nasal spray (fluticasone furoate), sometimes given to children with obstructive sleep apnea syndrome (OSAS), works on certain cells within a child's adenoids. We hypothesize that intranasal steroids lead to an upregulation of T regulatory cells in th...
What is the current status of trial NCT00603044?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2008-01. Estimated completion is 2009-08.
What interventions are being tested in trial NCT00603044?
The interventions under investigation include: fluticasone furoate (DRUG).
Who is sponsoring clinical trial NCT00603044?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00603044's enrollment target sits among peer trials
24 1699th of 2000 higher than 276 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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