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NCT00594867 · ClinicalTrials.gov registry record · Phase 4
The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers
A Phase 4 study, sponsored by University of Illinois at Chicago.
- Completed
- Registry status
- Phase 4
- Development phase
- 94
- Enrollment target
NCT00594867: Completed Phase 4 study, sponsored by University of Illinois at Chicago.
NCT00594867 is a Phase 4 study that has completed, run by University of Illinois at Chicago. The registered enrollment target is 94 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00594867, a Phase 4 study, has completed, sponsored by University of Illinois at Chicago.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 94 participants
- Enrollment target
Study Summary
Aspirin is a medication commonly used to relieve minor pains. Aspirin has also been used to prevent heart attacks and strokes. Aspirin, however, can also cause damage to the stomach and/or intestinal lining leading to the development of erosions ("small sores") and/or ulcers ("large sores"). Erosions may cause bleeding ("bleeding ulcers") and/or perforations ("holes in the stomach"). Acetaminophen, often referred by the brand name, Tylenol, is also used to treat minor pains but is not commonly recognized to cause damage to the stomach lining. Many patients often take both of these medications together. While the effects on the stomach lining of each medication, when used alone, are known, the effects of both medications, when used together, are not. The purpose of this study is to show whether or not the collective effects of both aspirin and acetaminophen, when used together, increase the damage on the stomach lining when compared to either medication alone.
Interventions
- DRUG Acetaminophen - 4 grams per day + Placebo
- DRUG Aspirin - 325 mg per day + Placebo
- DRUG Acetaminophen 4 gram per day + Aspirin 325 mg per day
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 94 participants |
| Start Date | 2006-12 |
| Est. Completion | 2007-12 |
| Phase | Phase 4 |
What the finished NCT00594867 record still lists
NCT00594867 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 94 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 3 interventions - of which Acetaminophen - 4 grams per day + Placebo is the first listed.
NCT00594867 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00594867 about?
NCT00594867 is a clinical study titled "The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers". Aspirin is a medication commonly used to relieve minor pains. Aspirin has also been used to prevent heart attacks and strokes. Aspirin, however, can also cause damage to the stomach and/or intestinal lining leading to the development of erosions ("small sores") and/or ulcers ("large sores"). Erosion...
What is the current status of trial NCT00594867?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 94 participants. The study started on 2006-12. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00594867?
The interventions under investigation include: Acetaminophen - 4 grams per day + Placebo (DRUG), Aspirin - 325 mg per day + Placebo (DRUG), Acetaminophen 4 gram per day + Aspirin 325 mg per day (DRUG).
Who is sponsoring clinical trial NCT00594867?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00594867's enrollment target sits among peer trials
94 871st of 2000 higher than 1,127 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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