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NCT00592501 · ClinicalTrials.gov registry record · Phase 2
Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma
A Phase 2 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
NCT00592501: Completed Phase 2 study, sponsored by Massachusetts General Hospital.
NCT00592501 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00592501, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
Study Summary
Photon beam radiation is the standard type of radiation used to treat nasopharyngeal carcinoma. Photon beam radiation enters the body and passes through healthy tissue, encounters the tumor and leaves the body through healthy tissue. Proton beam radiation has been shown to have the same effect on tumors as photon beam radiation but it enters the body, passes through healthy tissue, and encounters the tumor but then stops. This means less healthy tissue is affected by proton beam treatment than by photon beam treatment. The purpose of this study is to determine the effectiveness of proton beam radiation in treating nasopharyngeal cancer and reducing the acute and long-term side effects from the treatment. This study will also test to see if the sparing of the healthy tissue can improve quality of life
Primary Outcome
Acute toxicities are side affects that occur during treatment and 90 days after completion.
Interventions
- DRUG Cisplatin
- DRUG Fluorouracil
- RADIATION Proton/Photon Radiotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2006-10 |
| Est. Completion | 2019-04 |
| Phase | Phase 2 |
What the finished NCT00592501 record still lists
NCT00592501 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 3 interventions - of which Cisplatin is the first listed.
NCT00592501 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00592501 about?
NCT00592501 is a clinical study titled "Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma". Photon beam radiation is the standard type of radiation used to treat nasopharyngeal carcinoma. Photon beam radiation enters the body and passes through healthy tissue, encounters the tumor and leaves the body through healthy tissue. Proton beam radiation has been shown to have the same effect on tu...
What is the current status of trial NCT00592501?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2006-10. Estimated completion is 2019-04.
What interventions are being tested in trial NCT00592501?
The interventions under investigation include: Cisplatin (DRUG), Fluorouracil (DRUG), Proton/Photon Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT00592501?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00592501's enrollment target sits among peer trials
25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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