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NCT00588471 · ClinicalTrials.gov registry record · NA
Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention
A NA study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- NA
- Development phase
- 57
- Enrollment target
NCT00588471: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT00588471 is a NA study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 57 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00588471, a NA study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- NA
- Development phase
- 57 participants
- Enrollment target
Study Summary
The goal of this study is to determine if one dose of simvastatin will decrease the inflammatory response to coronary intervention. Also to determine if one dose of simvastatin affects endothelial function (activity of the artery) as measured by noninvasive peripheral artery tonography.
Primary Outcome
The hsCRP test evaluates vascular inflammation. People with higher hsCRP values have the highest risk of cardiovascular disease, and those with lower values have less of a risk. The American Heart Association and U.S. Centers for Disease Control and Prevention have defined risk groups as follows: Low risk: less than 1.0 mg/L Average risk: 1.0 to 3.0 mg/L High risk: above 3.0 mg/L
Interventions
- DRUG Placebo
- DRUG Simvastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 57 participants |
| Start Date | 2002-11 |
| Est. Completion | 2011-04 |
| Phase | NA |
Why NCT00588471 stopped before completion
NCT00588471 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 57 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00588471 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00588471 about?
NCT00588471 is a clinical study titled "Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention". The goal of this study is to determine if one dose of simvastatin will decrease the inflammatory response to coronary intervention. Also to determine if one dose of simvastatin affects endothelial function (activity of the artery) as measured by noninvasive peripheral artery tonography.
What is the current status of trial NCT00588471?
This trial is currently terminated. It is a NA study. The enrollment target is 57 participants. The study started on 2002-11. Estimated completion is 2011-04.
What interventions are being tested in trial NCT00588471?
The interventions under investigation include: Placebo (DRUG), Simvastatin (DRUG).
Who is sponsoring clinical trial NCT00588471?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00588471's enrollment target sits among peer trials
57 1261st of 2000 higher than 739 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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