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NCT00583700 · ClinicalTrials.gov registry record · Phase 2
Trental & Vitamin E for Radiation-Induced Fibrosis
A Phase 2 study, sponsored by University of Iowa.
- Completed
- Registry status
- Phase 2
- Development phase
- 54
- Enrollment target
NCT00583700: Completed Phase 2 study, sponsored by University of Iowa.
NCT00583700 is a Phase 2 study that has completed, run by University of Iowa. The registered enrollment target is 54 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00583700, a Phase 2 study, has completed, sponsored by University of Iowa.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 54 participants
- Enrollment target
Study Summary
This study seeks to determine if a combination of Trental and Vitamin E prevents the development of radiation fibrosis in women treated with radiation for the definitive management of their breast cancer.
Primary Outcome
A primary outcome of interest is the composite Subjective, Objective, Management, and Analytic (SOMA) score at 18-month follow-up visit. Maximum score is 45, with a score of 0 being ideal and representing no treatment-related side effects at the study visit.
Interventions
- DRUG Pentoxifylline
- DRUG Vitamin E
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2003-02 |
| Est. Completion | 2012-06 |
| Phase | Phase 2 |
What the finished NCT00583700 record still lists
NCT00583700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower).
The record links to 0 conditions, and to 2 interventions - of which Pentoxifylline is the first listed.
NCT00583700 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00583700 about?
NCT00583700 is a clinical study titled "Trental & Vitamin E for Radiation-Induced Fibrosis". This study seeks to determine if a combination of Trental and Vitamin E prevents the development of radiation fibrosis in women treated with radiation for the definitive management of their breast cancer.
What is the current status of trial NCT00583700?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 54 participants. The study started on 2003-02. Estimated completion is 2012-06.
What interventions are being tested in trial NCT00583700?
The interventions under investigation include: Pentoxifylline (DRUG), Vitamin E (DRUG).
Who is sponsoring clinical trial NCT00583700?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00583700's enrollment target sits among peer trials
54 1160th of 2000 higher than 830 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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