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NCT00580814 · ClinicalTrials.gov registry record · NA
Brain Dopamine Function in Adults With ADHD
A NA study, sponsored by University of California, Irvine.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
NCT00580814: Completed NA study, sponsored by University of California, Irvine.
NCT00580814 is a NA study that has completed, run by University of California, Irvine. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00580814, a NA study, has completed, sponsored by University of California, Irvine.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
Study Summary
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and dopamine transporter levels in ADHD subjects.
Primary Outcome
Striatal DAT availability as noted in PET scans post one year of methylphenidate treatment or no intervention. The unit listed as binding potential (BPND) was measured with a dynamic PET scan protocol, using carbon-11 labeled cocaine, a radioligand with specific binding to DAT (which is inhibited by drugs that block DAT but not by drugs that block the norephephrine or serotonin transporters). This radiotracer was utilized to quantify DAT availability as non-displaceable binding potential using
Interventions
- DRUG Experimental: methylphenidate treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2006-02 |
| Est. Completion | 2009-04 |
| Phase | NA |
What the finished NCT00580814 record still lists
NCT00580814 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Experimental: methylphenidate treatment is the first listed.
NCT00580814 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00580814 about?
NCT00580814 is a clinical study titled "Brain Dopamine Function in Adults With ADHD". The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and dopamine transporter levels in ADHD subjects.
What is the current status of trial NCT00580814?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2006-02. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00580814?
The interventions under investigation include: Experimental: methylphenidate treatment (DRUG).
Who is sponsoring clinical trial NCT00580814?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00580814's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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