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NCT00580645 · ClinicalTrials.gov registry record · Phase 2
Do Treatments for Smoking Cessation Affect Alcohol Drinking?
A Phase 2 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT00580645: Completed Phase 2 study, sponsored by Yale University.
NCT00580645 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00580645, a Phase 2 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effect of smoking cessation medications on alcohol drinking. Effect of 2mg/day, 1mg/day, placebo varenicline was evaluated. Following 7 days of medication pre-treatment to achieve steady state levels, participants complete a laboratory session assessing alcohol self-administration behavior. Study enrolls heavy drinking smokers (not tested under nicotine deprivation), non-daily smokers, and nonsmokers. Volunteers are administered either varenicline (Chantix) or placebo.
Primary Outcome
number of drinks consumed during hour 1 and hour 2 of the 120 minute alcohol self-administration session
Interventions
- DRUG placebo
- DRUG varenicline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2007-04 |
| Est. Completion | 2016-11 |
| Phase | Phase 2 |
What the finished NCT00580645 record still lists
NCT00580645 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT00580645 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00580645 about?
NCT00580645 is a clinical study titled "Do Treatments for Smoking Cessation Affect Alcohol Drinking?". The purpose of this study is to examine the effect of smoking cessation medications on alcohol drinking. Effect of 2mg/day, 1mg/day, placebo varenicline was evaluated. Following 7 days of medication pre-treatment to achieve steady state levels, participants complete a laboratory session assessing a...
What is the current status of trial NCT00580645?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2007-04. Estimated completion is 2016-11.
What interventions are being tested in trial NCT00580645?
The interventions under investigation include: placebo (DRUG), varenicline (DRUG).
Who is sponsoring clinical trial NCT00580645?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00580645's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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