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NCT00580619 · ClinicalTrials.gov registry record · Phase 1
Autonomic Nervous System and Chronic Fatigue Syndrome
A Phase 1 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 1
- Development phase
- 170
- Enrollment target
NCT00580619 is a Phase 1 study that has completed, run by Vanderbilt University. The registered enrollment target is 170 participants.
The verdict
NCT00580619, a Phase 1 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 170 participants
- Enrollment target
Study Summary
The investigators propose to test the hypothesis that the sympathetic nervous system contributes to the cardiovascular and inflammatory abnormalities present in the chronic fatigue syndrome (CFS) and, in particular in the subset of patients characterized by postural tachycardia syndrome (POTS). CFS and POTS are seen mostly in otherwise normal young women, and are the cause of significant disability. A substantial proportion of patients referred for evaluation of POTS met diagnostic criteria for CFS and, conversely, a subset of patients referred for treatment for CFS have POTS. The investigators hypothesize that sympathetic activation underlies the pathophysiology of patients in whom CFS and POTS overlap (CFS-P).
Interventions
- OTHER Autonomic Function Testing
- OTHER Saline infusions
- DRUG L-NMMA trimethaphan
- DRUG methyldopa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2007-04 |
| Est. Completion | 2017-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00580619
The ClinicalTrials.gov registry entry for NCT00580619 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 170 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Autonomic Function Testing is the first listed.
NCT00580619 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00580619 about?
NCT00580619 is a clinical study titled "Autonomic Nervous System and Chronic Fatigue Syndrome". The investigators propose to test the hypothesis that the sympathetic nervous system contributes to the cardiovascular and inflammatory abnormalities present in the chronic fatigue syndrome (CFS) and, in particular in the subset of patients characterized by postural tachycardia syndrome (POTS). CFS ...
What is the current status of trial NCT00580619?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 170 participants. The study started on 2007-04. Estimated completion is 2017-01.
What interventions are being tested in trial NCT00580619?
The interventions under investigation include: Autonomic Function Testing (OTHER), Saline infusions (OTHER), L-NMMA trimethaphan (DRUG), methyldopa (DRUG).
Who is sponsoring clinical trial NCT00580619?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
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