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NCT00579644 · ClinicalTrials.gov registry record · Phase 3
Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone
A Phase 3 study, sponsored by University of Nebraska.
- Completed
- Registry status
- Phase 3
- Development phase
- 91
- Enrollment target
NCT00579644: Completed Phase 3 study, sponsored by University of Nebraska.
NCT00579644 is a Phase 3 study that has completed, run by University of Nebraska. The registered enrollment target is 91 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00579644, a Phase 3 study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 91 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if a combination of methotrexate and minocycline works better than methotrexate alone in early Rheumatoid Arthritis
Primary Outcome
Patients will be evaluated and then at 2-month intervals to 12 months using the ACR core set of outcome variables (50) for remission. Additionally hand x-rays will be done.
Interventions
- DRUG methotrexate
- DRUG Combination of Minocycline and MTX or MTX alone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 91 participants |
| Start Date | 2001-03-28 |
| Est. Completion | 2006-05-31 |
| Phase | Phase 3 |
What the finished NCT00579644 record still lists
NCT00579644 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 91 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 2 interventions - of which methotrexate is the first listed.
NCT00579644 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00579644 about?
NCT00579644 is a clinical study titled "Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone". The purpose of this study is to determine if a combination of methotrexate and minocycline works better than methotrexate alone in early Rheumatoid Arthritis
What is the current status of trial NCT00579644?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 91 participants. The study started on 2001-03-28. Estimated completion is 2006-05-31.
What interventions are being tested in trial NCT00579644?
The interventions under investigation include: methotrexate (DRUG), Combination of Minocycline and MTX or MTX alone (DRUG).
Who is sponsoring clinical trial NCT00579644?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00579644's enrollment target sits among peer trials
91 1724th of 2000 higher than 277 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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