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NCT00575939 · ClinicalTrials.gov registry record
Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV
A clinical trial, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- 120
- Enrollment target
NCT00575939: Completed study, sponsored by University Hospitals Cleveland Medical Center.
NCT00575939 is a clinical trial that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 120 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00575939 has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- 120 participants
- Enrollment target
Study Summary
It is well known that HIV-infected subjects frequently experience hyperlipidemias, insulin resistance, and visceral adiposity, which are known to increase the risk of atherosclerosis. Several cohorts have shown an increased risk of heart disease in people with HIV. The effect of HIV treatment versus HIV itself on the incidence of heart disease is unclear. In this study the investigators will assess the effect on carotid IMT of the initiation of antiretroviral combinations that are known to have a minimal effect on lipids and insulin resistance. We will also assess the changes in several inflammation and cardiovascular markers,as well as endothelial activation markers,and how these changes relate to therapy-induced changes in immunologic, virologic and metabolic markers.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2007-11 |
| Est. Completion | 2014-11 |
What the finished NCT00575939 record still lists
NCT00575939 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00575939 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00575939 about?
NCT00575939 is a clinical study titled "Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV". It is well known that HIV-infected subjects frequently experience hyperlipidemias, insulin resistance, and visceral adiposity, which are known to increase the risk of atherosclerosis. Several cohorts have shown an increased risk of heart disease in people with HIV. The effect of HIV treatment versus...
What is the current status of trial NCT00575939?
This trial is currently completed. The enrollment target is 120 participants. The study started on 2007-11. Estimated completion is 2014-11.
Who is sponsoring clinical trial NCT00575939?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
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