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NCT00573365 · ClinicalTrials.gov registry record · NA
LED Photomodulation for Prevention of Post-Radiation Treatment Dermatitis
A NA study, sponsored by University of California, Irvine.
- Completed
- Registry status
- NA
- Development phase
- 33
- Enrollment target
NCT00573365: Completed NA study, sponsored by University of California, Irvine.
NCT00573365 is a NA study that has completed, run by University of California, Irvine. The registered enrollment target is 33 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00573365, a NA study, has completed, sponsored by University of California, Irvine.
- COMPLETED
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
Study Summary
Radiation dermatitis is a common side-effect of radiation therapy in cancer patients who frequently can experience redness, pain, crusting, and even ulceration of the skin causing suffering and treatment interruption. A recent retrospective study by DeLand demonstrated that administering light emitting diode (LED) photomodulation after each radiation treatment for breast cancer decreased radiation dermatitis in a majority of patients. LED photomodulation is a process by which specific sequences of light are used to regulate or manipulate cell activity without causing heat or damage to the skin. Each LED treatment is painless and is completed in usually less than one minute. LED photomodulation may reduce the suffering associated with radiation treatments, improve cosmetic outcome in radiation fields, and eliminate breaks in radiation treatments which may be required because of severe ulcerating reactions. This study will attempt to replicate the findings of Dr. DeLand's study by randomly assigning at least 40 breast cancer patients to either a treatment group or to a control group. The treatment group will receive LED photomodulation treatments before and after each radiation treatment with the Gentlewaves Select™ handheld high energy 590nm LED array using specific sequences of pulses used in other studies; the treatment group will also receive 7 additional treatments over 2 weeks after their radiation treatment course is completed. The control group will receive no LED treatment but will use the exact same skin care regimen as the treatment group. In addition to weekly evaluation and grading of skin reactions, subjects will be photographed under standardized conditions weekly and then photographs will be evaluated and graded by blinded dermatologists.
Interventions
- RADIATION Radiation
- DEVICE Gentlewaves Select™ handheld high energy LED array
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2007-03 |
| Est. Completion | 2008-08 |
| Phase | NA |
What the finished NCT00573365 record still lists
NCT00573365 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Radiation is the first listed.
NCT00573365 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00573365 about?
NCT00573365 is a clinical study titled "LED Photomodulation for Prevention of Post-Radiation Treatment Dermatitis". Radiation dermatitis is a common side-effect of radiation therapy in cancer patients who frequently can experience redness, pain, crusting, and even ulceration of the skin causing suffering and treatment interruption. A recent retrospective study by DeLand demonstrated that administering light emitt...
What is the current status of trial NCT00573365?
This trial is currently completed. It is a NA study. The enrollment target is 33 participants. The study started on 2007-03. Estimated completion is 2008-08.
What interventions are being tested in trial NCT00573365?
The interventions under investigation include: Radiation (RADIATION), Gentlewaves Select™ handheld high energy LED array (DEVICE).
Who is sponsoring clinical trial NCT00573365?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00573365's enrollment target sits among peer trials
33 1574th of 2000 higher than 423 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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