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NCT00558727 · ClinicalTrials.gov registry record · Phase 1

Study of RH-1 in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

A Phase 1 study, sponsored by Spectrum Pharmaceuticals.

Terminated
Registry status
Phase 1
Development phase
12
Enrollment target

NCT00558727: Clinical Trial Phase 1 study, sponsored by Spectrum Pharmaceuticals.

NCT00558727 is a Phase 1 study that was terminated before completion, run by Spectrum Pharmaceuticals. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00558727, a Phase 1 study, was terminated before completion, sponsored by Spectrum Pharmaceuticals.

TERMINATED
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

This is a Phase 1, nonrandomized, open-label, dose-escalation study of 3-hour IV infusions of RH-1 administered to patients with advanced solid tumors or non-Hodgkin's lymphoma (NHL). Treatment will continue until a patient meets criteria for discontinuation.

Interventions

  • DRUG RH-1

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2007-11
Est. Completion 2008-12
Phase Phase 1
Spectrum Pharmaceuticals

52 total trials

Why NCT00558727 stopped before completion

NCT00558727 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 1 intervention - of which RH-1 is the first listed.

NCT00558727 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00558727 about?

NCT00558727 is a clinical study titled "Study of RH-1 in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma". This is a Phase 1, nonrandomized, open-label, dose-escalation study of 3-hour IV infusions of RH-1 administered to patients with advanced solid tumors or non-Hodgkin's lymphoma (NHL). Treatment will continue until a patient meets criteria for discontinuation.

What is the current status of trial NCT00558727?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2007-11. Estimated completion is 2008-12.

What interventions are being tested in trial NCT00558727?

The interventions under investigation include: RH-1 (DRUG).

Who is sponsoring clinical trial NCT00558727?

This trial is sponsored by Spectrum Pharmaceuticals, which has 52 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00558727's enrollment target sits among peer trials

12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00558727, the US trial registry maintained by the National Library of Medicine. NCT00558727 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.