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NCT00547196 · ClinicalTrials.gov registry record · NA
AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders
A NA study, sponsored by City of Hope Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT00547196: Completed NA study, sponsored by City of Hope Medical Center.
NCT00547196 is a NA study that has completed, run by City of Hope Medical Center. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00547196, a NA study, has completed, sponsored by City of Hope Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
RATIONALE: Giving chemotherapy with or without total-body irradiation before a donor umbilical cord blood transplant helps stop the growth of cancer or abnormal cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving cyclosporine and mycophenolate mofetil before and after transplant may stop this from happening. PURPOSE: This clinical trial is studying how well four different chemotherapy regimens given with or without total-body irradiation before umbilical cord blood transplant work in treating patients with relapsed or refractory hematologic cancer.
Primary Outcome
Number of surviving patients at Day 100 post-transplant divided by number of patients undergone transplantation.
Interventions
- DRUG Cyclophosphamide
- DRUG Busulfan
- DRUG Fludarabine phosphate
- DRUG Cyclosporine
- BIOLOGICAL filgrastim
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2005-08-16 |
| Est. Completion | 2024-05-28 |
| Phase | NA |
What the finished NCT00547196 record still lists
NCT00547196 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.
NCT00547196 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00547196 about?
NCT00547196 is a clinical study titled "AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders". RATIONALE: Giving chemotherapy with or without total-body irradiation before a donor umbilical cord blood transplant helps stop the growth of cancer or abnormal cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the stem cells from a donor are infused i...
What is the current status of trial NCT00547196?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2005-08-16. Estimated completion is 2024-05-28.
What interventions are being tested in trial NCT00547196?
The interventions under investigation include: Cyclophosphamide (DRUG), Busulfan (DRUG), Fludarabine phosphate (DRUG), Cyclosporine (DRUG), filgrastim (BIOLOGICAL).
Who is sponsoring clinical trial NCT00547196?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00547196's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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