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NCT00540774 · ClinicalTrials.gov registry record · NA
Optical Sensor for Photodynamic Detection of Oral Pathology
A NA study, sponsored by University of California, Irvine.
- Completed
- Registry status
- NA
- Development phase
- 1,004
- Enrollment target
NCT00540774: Completed NA study, sponsored by University of California, Irvine.
NCT00540774 is a NA study that has completed, run by University of California, Irvine. The registered enrollment target is 1,004 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (28% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00540774, a NA study, has completed, sponsored by University of California, Irvine.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,004 participants
- Enrollment target
Study Summary
Overall objective of this work is to develop better ways of detecting, diagnosing and measuring oral diseases and structures using light and optical approaches. All different areas of the mouth will be imaged, including healthy, diseased, dysplastic and malignant, as well as oral biofilm, and the imaging data compared against conventional diagnostic approaches such clinical and histopathological and molecular evaluations to (1) gain a better understanding of processes involved in oral pathology and (2) develop a combined patient specific, non-invasive method for the detection, diagnosis and screening of oral pathology and biofilm. Thus our goal is to identify and evaluate microstructural, metabolic, vascular, protein, genomic and metabolomics biomarkers of oral pathology can be used to detect, predict and map oral pathology, especially neoplasia. We are recruiting patients with a wide range of oral conditions including plaque, dry mouth, toothache, root canal treatments, gum disease, oral sores, dysplasia and cancer, autoimmune conditions and others as well as healthy control subjects. We will use a range of non-invasive imaging modalities to obtain information on the ways in which the oral health status affects optical properties, and determine means of detecting and quantifying these factors.. Imaging modalities to be utilized include: 1. Coherence and Doppler Tomography 2. Laser Speckle Imaging 3. Various forms of Spectroscopy 4. Fluorescence
Primary Outcome
Develop a non-invasive tool for the detection, diagnosis and screening of oral pathology and understanding of processes involved in oral pathology
Interventions
- DEVICE detection of oral pathology
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,004 participants |
| Start Date | 2003-04 |
| Est. Completion | 2026-03-03 |
| Phase | NA |
What the finished NCT00540774 record still lists
NCT00540774 is an interventional study that assigns participants to a tested intervention. Its 1,004 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (28% lower).
The record links to 0 conditions, and to 1 intervention - of which detection of oral pathology is the first listed.
NCT00540774 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00540774 about?
NCT00540774 is a clinical study titled "Optical Sensor for Photodynamic Detection of Oral Pathology". Overall objective of this work is to develop better ways of detecting, diagnosing and measuring oral diseases and structures using light and optical approaches. All different areas of the mouth will be imaged, including healthy, diseased, dysplastic and malignant, as well as oral biofilm, and the im...
What is the current status of trial NCT00540774?
This trial is currently completed. It is a NA study. The enrollment target is 1,004 participants. The study started on 2003-04. Estimated completion is 2026-03-03.
What interventions are being tested in trial NCT00540774?
The interventions under investigation include: detection of oral pathology (DEVICE).
Who is sponsoring clinical trial NCT00540774?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00540774's enrollment target sits among peer trials
1,004 106th of 2000 higher than 1,895 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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