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NCT00530816 · ClinicalTrials.gov registry record · Phase 2

Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

A Phase 2 study, sponsored by Amgen.

Completed
Registry status
Phase 2
Development phase
164
Enrollment target

NCT00530816: Completed Phase 2 study, sponsored by Amgen.

NCT00530816 is a Phase 2 study that has completed, run by Amgen. The registered enrollment target is 164 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00530816, a Phase 2 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 2
Development phase
164 participants
Enrollment target

Study Summary

To evaluate the best overall response rate, safety and tolerability of carfilzomib in patients with relapsed or refractory multiple myeloma.

Primary Outcome

ORR is defined as the percentage of patients who achieved a best response of stringent complete response (sCR), complete response (CR), very good partial response (VGPR) or partial response (PR) determined by Independent Review Committee (IRC). Responses were assessed according to International Uniform Response Criteria for Multiple Myeloma, documented by 2 consecutive assessments made at any time before the start of new therapy. sCR: CR as defined below plus normal FLC ratio and absence of clo

Interventions

  • DRUG carfilzomib

Trial Details

FieldValue
Enrollment Target 164 participants
Start Date 2007-09
Est. Completion 2013-07
Phase Phase 2
Amgen

558 total trials

What the finished NCT00530816 record still lists

NCT00530816 is an interventional study that assigns participants to a tested intervention. The registered 164 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher).

The record links to 0 conditions, and to 1 intervention - of which carfilzomib is the first listed.

NCT00530816 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00530816 about?

NCT00530816 is a clinical study titled "Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma". To evaluate the best overall response rate, safety and tolerability of carfilzomib in patients with relapsed or refractory multiple myeloma.

What is the current status of trial NCT00530816?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 164 participants. The study started on 2007-09. Estimated completion is 2013-07.

What interventions are being tested in trial NCT00530816?

The interventions under investigation include: carfilzomib (DRUG).

Who is sponsoring clinical trial NCT00530816?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00530816's enrollment target sits among peer trials

164 413th of 2000 higher than 1,583 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00530816, the US trial registry maintained by the National Library of Medicine. NCT00530816 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.