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NCT00527618 · ClinicalTrials.gov registry record · Phase 4

Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV

A Phase 4 study, sponsored by University of Washington.

Completed
Registry status
Phase 4
Development phase
28
Enrollment target

NCT00527618 is a Phase 4 study that has completed, run by University of Washington. The registered enrollment target is 28 participants.

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The verdict

NCT00527618, a Phase 4 study, has completed, sponsored by University of Washington.

COMPLETED
Registry status
Phase 4
Development phase
28 participants
Enrollment target

Study Summary

To compare the effect of high-dose valacyclovir (1 gram orally twice daily) versus standard-dose acyclovir (400 mg orally twice daily) on the frequency of genital HSV reactivation and on plasma HIV-1 levels among HSV-2/HIV-1 co-infected individuals. The investigators hypothesize that high-dose valacyclovir will result in greater reduction in plasma HIV-1 and genital HSV reactivation.

Interventions

  • DRUG valacyclovir
  • DRUG acyclovir

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2007-12
Est. Completion 2011-03
Phase Phase 4

Sponsor

University of Washington

1,048 total trials

What the Registry Record Tells You About NCT00527618

The ClinicalTrials.gov registry entry for NCT00527618 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which valacyclovir is the first listed.

NCT00527618 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00527618 about?

NCT00527618 is a clinical study titled "Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV". To compare the effect of high-dose valacyclovir (1 gram orally twice daily) versus standard-dose acyclovir (400 mg orally twice daily) on the frequency of genital HSV reactivation and on plasma HIV-1 levels among HSV-2/HIV-1 co-infected individuals. The investigators hypothesize that high-dose valac...

What is the current status of trial NCT00527618?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 28 participants. The study started on 2007-12. Estimated completion is 2011-03.

What interventions are being tested in trial NCT00527618?

The interventions under investigation include: valacyclovir (DRUG), acyclovir (DRUG).

Who is sponsoring clinical trial NCT00527618?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.